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Objective <p>This research aimed to evaluate the epidemiological and clinical characteristics of ventilator-associated events (VAE) using the CDC framework in a tertiary hospital in Moscow, Russia.</p> Results <p>In this cohort study, we analyzed electronic health records from 407 mechanically ventilated adults who were admitted to the Kommunarka Moscow Multipurpose Clinical Center between September 2022 and December 2023. We identified a total of 35 VAE, resulting in an incidence rate of 8.39 (95% confidence interval, 5.84 to 11.67) events per 1,000 ventilator-days. The presence of VAE was associated with higher ICU mortality by day 30 from the start of mechanical ventilation (adjusted hazard ratio, 1.58; 95% confidence interval, 1.01 to 2.48), particularly in patients with infection-related ventilator-associated complications (adjusted hazard ratio, 2.09; 95% confidence interval, 1.17 to 3.74). The median durations of mechanical ventilation and ICU length of stay were comparable between patients with VAE and those without. Implementing surveillance measures and developing tailored preventive strategies for VAE may be beneficial in similar healthcare settings to improve outcomes for mechanically ventilated patients.</p>

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Incidence and clinical outcomes of ventilator-associated events in Russian tertiary care settings: an analysis of electronic health records

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月15日

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  • Sergei Vladimirov,
  • Ilia Klimenko,
  • Nikita Matiushkov,
  • Denis Protsenko,
  • Dmitry Sergeev

摘要

Objective

This research aimed to evaluate the epidemiological and clinical characteristics of ventilator-associated events (VAE) using the CDC framework in a tertiary hospital in Moscow, Russia.

Results

In this cohort study, we analyzed electronic health records from 407 mechanically ventilated adults who were admitted to the Kommunarka Moscow Multipurpose Clinical Center between September 2022 and December 2023. We identified a total of 35 VAE, resulting in an incidence rate of 8.39 (95% confidence interval, 5.84 to 11.67) events per 1,000 ventilator-days. The presence of VAE was associated with higher ICU mortality by day 30 from the start of mechanical ventilation (adjusted hazard ratio, 1.58; 95% confidence interval, 1.01 to 2.48), particularly in patients with infection-related ventilator-associated complications (adjusted hazard ratio, 2.09; 95% confidence interval, 1.17 to 3.74). The median durations of mechanical ventilation and ICU length of stay were comparable between patients with VAE and those without. Implementing surveillance measures and developing tailored preventive strategies for VAE may be beneficial in similar healthcare settings to improve outcomes for mechanically ventilated patients.