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Background <p>Although physical exercise is an evidence-based treatment for patients with chronic diseases, providing benefits in terms of morbidity, mortality and quality of life, its implementation in real-world healthcare systems is still limited. Even when physicians recommend physical activity, compliance and adherence to exercise programs remain very low. This study aims to implement a real-world model for tailored exercise prescription (TEP) in an outpatient clinic to evaluate feasibility, effectiveness, compliance and adherence.</p> Methods <p>A TEP was set for each participant, based on a complete clinical and functional evaluation including cardiopulmonary exercise testing and fitness test battery. Subsequent supervised training sessions (STS) were performed for at least 6&#xa0;weeks. After 6&#xa0;months functional evaluations were repeated, also assessing compliance with general recommendations and adherence to the prescribed exercise program.</p> Results <p>A total of 312 patients (44% male) with a mean age of 52.1 ± 13.6&#xa0;years were enrolled. The most frequent main chronic conditions were obesity (47%), solid organ transplantation (32%), primary cardiovascular diseases (8%) and cancer (4%). The initial STS program was completed by 85.9% of patients, all without adverse events. Patient compliance, measured as attendance at the follow-up meeting, was 53.2%, while adherence to the TEP during the 6-month program was 44.9%.</p> Conclusion <p>A real-word model for TEP followed by a period of STS is feasible in patients with chronic diseases in a real outpatient clinical setting. However, intervention strategies based on behavioral change and motivation are needed to foster greater compliance and adherence in the mid-to-long term.</p>

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From theory into practice: insights from a real-world implementation model for tailored exercise prescription in chronic diseases

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年12月29日

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  • Federica Duregon,
  • Giulia Quinto,
  • Marco Vecchiato,
  • Sara Faggian,
  • Nicola Borasio,
  • Veronica Baioccato,
  • Sara Ortolan,
  • Andrea Gasperetti,
  • Andrea Ermolao,
  • Daniel Neunhaeuserer,
  • Francesca Battista

摘要

Background

Although physical exercise is an evidence-based treatment for patients with chronic diseases, providing benefits in terms of morbidity, mortality and quality of life, its implementation in real-world healthcare systems is still limited. Even when physicians recommend physical activity, compliance and adherence to exercise programs remain very low. This study aims to implement a real-world model for tailored exercise prescription (TEP) in an outpatient clinic to evaluate feasibility, effectiveness, compliance and adherence.

Methods

A TEP was set for each participant, based on a complete clinical and functional evaluation including cardiopulmonary exercise testing and fitness test battery. Subsequent supervised training sessions (STS) were performed for at least 6 weeks. After 6 months functional evaluations were repeated, also assessing compliance with general recommendations and adherence to the prescribed exercise program.

Results

A total of 312 patients (44% male) with a mean age of 52.1 ± 13.6 years were enrolled. The most frequent main chronic conditions were obesity (47%), solid organ transplantation (32%), primary cardiovascular diseases (8%) and cancer (4%). The initial STS program was completed by 85.9% of patients, all without adverse events. Patient compliance, measured as attendance at the follow-up meeting, was 53.2%, while adherence to the TEP during the 6-month program was 44.9%.

Conclusion

A real-word model for TEP followed by a period of STS is feasible in patients with chronic diseases in a real outpatient clinical setting. However, intervention strategies based on behavioral change and motivation are needed to foster greater compliance and adherence in the mid-to-long term.