Background <p>Sitting volleyball relies heavily on upper-body strength and anaerobic capacity. Serve, spike, and speed-endurance are decisive skills, yet the ergogenic potential of low-dose caffeine in this Paralympic sport remains unclear.</p> Purpose <p>To examine the acute effects of low-dose caffeine (3&#xa0;mg/kg) supplementation on serve speed, spike speed, and speed-endurance in elite sitting volleyball players.</p> Methods <p>Using a randomized, double-blind, crossover design, 13 elite male athletes from the Turkish National Sitting Volleyball Team completed serve speed, spike speed, and speed-endurance tests under caffeine (CAF) and placebo (PLA) conditions.</p> Results <p>Caffeine intake produced a moderate improvement in serve speed (<i>p</i> = 0.028, d = 0.460); however, this effect did not remain statistically significant after Bonferroni correction (adjusted <i>p</i> = 0.084). No significant effects were observed for spike speed (<i>p</i> = 0.547, d = 0.166) or speed-endurance performance (<i>p</i> = 0.709, d = 0.111). Perceived exertion during the speed-endurance test was similarly high in both conditions.</p> Conclusions <p>Low-dose caffeine may offer a trend toward improved serve performance, but the effect was not robust after statistical adjustment, and no benefits were observed for spike speed or speed-endurance. These findings highlight that caffeine’s ergogenic effects are context-dependent and shaped by task complexity and sport-specific motor demands. Further research with larger and more diverse samples, genotype-based subgroups, and varied dosing strategies is warranted to clarify caffeine’s role in adaptive sports.</p> Trial registration <p>The randomized controlled trial was retrospectively registered on 21/06/2025 at ClinicalTrials.gov, under the registration number NCT07056231.</p>