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<p>This study evaluates the electrochemical performance of 316&#xa0;L stainless steel alloy as a potential ureteral stent material in a synthetic urine environment mimicking conditions of <i>Candida</i>-associated urinary tract infections. The electrochemical behavior was investigated using electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and potentiodynamic polarization techniques, both in the presence and absence of <i>Candida albicans</i>. Results demonstrated that the formation of a biofilm by <i>Candida albicans</i> significantly influences the corrosion behavior of the alloy, as evidenced by changes in electrochemical parameters. Surface morphology and microbial adhesion were further confirmed through scanning electron microscopy (SEM), revealing biofilm development on the alloy’s surface. These findings highlight the critical role of fungal colonization in the degradation and stability of metallic ureteral stents under infection conditions.</p>

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Electrochemical evaluation of stainless steel alloy as a ureteral stent in synthetic urine solution in-vitro with Candida urinary tract infection

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月26日

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  • Salma Mamdouh,
  • Renad S. El-Kamel,
  • Amany M. Fekry,
  • Magda A. Ameer

摘要

This study evaluates the electrochemical performance of 316 L stainless steel alloy as a potential ureteral stent material in a synthetic urine environment mimicking conditions of Candida-associated urinary tract infections. The electrochemical behavior was investigated using electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and potentiodynamic polarization techniques, both in the presence and absence of Candida albicans. Results demonstrated that the formation of a biofilm by Candida albicans significantly influences the corrosion behavior of the alloy, as evidenced by changes in electrochemical parameters. Surface morphology and microbial adhesion were further confirmed through scanning electron microscopy (SEM), revealing biofilm development on the alloy’s surface. These findings highlight the critical role of fungal colonization in the degradation and stability of metallic ureteral stents under infection conditions.