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<p>In a cohort of 109 adults resuscitated from out-of-hospital cardiac arrest and admitted to a tertiary intensive care unit (ICU), non-survivors showed higher mean fluid intake, reduced urine output, and greater cumulative positive fluid balance during the first 96&#xa0;h after resuscitation. Daily increases in mean fluid balance were independently associated with ICU mortality after adjustment for confounding factors. These observations suggest that sustained positive fluid balance is linked to adverse outcomes, underscoring the potential value of more individualized or restrictive fluid management following cardiac arrest.&#xa0;</p>

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Tipping the balance: early post-resuscitation fluid accumulation and outcome after cardiac arrest

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月25日

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  • Chiara Crivellari,
  • Aurora Magliocca,
  • Cristina Dulama,
  • Giulia Merigo,
  • Fabiana Madotto,
  • Mauro Panigada,
  • Giacomo Grasselli,
  • Giuseppe Ristagno

摘要

In a cohort of 109 adults resuscitated from out-of-hospital cardiac arrest and admitted to a tertiary intensive care unit (ICU), non-survivors showed higher mean fluid intake, reduced urine output, and greater cumulative positive fluid balance during the first 96 h after resuscitation. Daily increases in mean fluid balance were independently associated with ICU mortality after adjustment for confounding factors. These observations suggest that sustained positive fluid balance is linked to adverse outcomes, underscoring the potential value of more individualized or restrictive fluid management following cardiac arrest.