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<p>While APP is largely neuonally expressed, Aβ amyloid is largely produced by microglia as the clearance mechanisms for damaged membranes becomes overwhelmed.</p>

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Evidence suggesting that microglia make amyloid from neuronally expressed APP: a hypothesis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年5月9日

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  • John Hardy,
  • Patrick Lewis

摘要

While APP is largely neuonally expressed, Aβ amyloid is largely produced by microglia as the clearance mechanisms for damaged membranes becomes overwhelmed.