<p>The objective of this study was to assess the demographic characteristics and impact on quality of life (QoL) of patients with PPG in France through a multicentre study. The results of the study are as follows: The PRO [PUSH-D, PHQ-9 et GAD-7] revealed that more than half of the patients exhibited a significant impact on their quality of life. High scores for fatigue, stress, skin and joint pain were reported, with 65% of patients at risk of mild to severe depression. The clinical burden was also assessed. A total of 48.8% of patients were hospitalised, while 39% took sick leave. This study is the first to assess the PUSH-D, PHQ-9 and GAD-7 scores in patients with PPG, which highlighted a significant clinical burden and negative impact on their daily lives.</p>

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Generalized pustular psoriasis: a multicentric study on patient characteristics and clinical burden

  • Cristina Bulai Livideanu,
  • Jérémy Gottlieb,
  • Denis Jullien,
  • Thierry Passeron,
  • Sophie Vildy,
  • Emmanuel Delaporte,
  • Carle Paul,
  • Julien Chollet,
  • Marie Najean,
  • Denis San,
  • Charles Taieb,
  • Bénédicte Charles,
  • Emmanuel Mahe,
  • Pierre-André Becherel,
  • Laurent Misery

摘要

The objective of this study was to assess the demographic characteristics and impact on quality of life (QoL) of patients with PPG in France through a multicentre study. The results of the study are as follows: The PRO [PUSH-D, PHQ-9 et GAD-7] revealed that more than half of the patients exhibited a significant impact on their quality of life. High scores for fatigue, stress, skin and joint pain were reported, with 65% of patients at risk of mild to severe depression. The clinical burden was also assessed. A total of 48.8% of patients were hospitalised, while 39% took sick leave. This study is the first to assess the PUSH-D, PHQ-9 and GAD-7 scores in patients with PPG, which highlighted a significant clinical burden and negative impact on their daily lives.