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Objectives <p>This study compared conventional preoperative parameters between transcatheter aortic valve replacement (TAVR) patients with and without post-procedural new-onset atrial fibrillation (NOAF) to identify simple risk markers.</p> Methods <p>A total of 211 patients undergoing TAVR were enrolled. Post-procedural NOAF occurred in 19 patients (9.0%). Preoperative clinical baseline data, electrocardiographic parameters, conventional echocardiographic indices, laboratory findings, and perioperative variables were compared between the NOAF and No-NOAF groups.</p> Results <p>Compared with the No-NOAF group, patients with post-TAVR NOAF were significantly older (<i>P</i> = 0.002) and had a higher heart rate (<i>P</i> = 0.002). Echocardiographically, the NOAF group exhibited larger cardiac dimensions, including right ventricular diameter (<i>P</i> &lt; 0.001), pulmonary artery diameter (<i>P</i> = 0.003), right atrial transverse diameter (<i>P</i> &lt; 0.001), left atrial diameter (<i>P</i> = 0.042), and left ventricular diameter (<i>P</i> = 0.018). Moreover, the NOAF group had lower left ventricular ejection fraction (<i>P</i> = 0.005) and fractional shortening (<i>P</i> = 0.006). Laboratory findings showed significantly higher levels of indirect bilirubin, serum creatinine, uric acid, monocyte percentage, and N-terminal pro-brain natriuretic peptide (NT-proBNP) (<i>P</i> &lt; 0.001), as well as lower glomerular filtration rate and total cholesterol (<i>P</i> = 0.009) in the NOAF group. No significant differences were observed in procedure length, valve type, or intraoperative complications (<i>P</i> &gt; 0.05).</p> Conclusions <p>Older age, higher heart rate, enlarged cardiac chambers (including right heart and left atrium), reduced left ventricular systolic function, elevated NT-proBNP, renal dysfunction, higher uric acid, lower total cholesterol, and increased monocyte percentage are associated with post-TAVR NOAF. These easily accessible conventional markers may facilitate early identification of high-risk patients in routine clinical practice, offering a practical alternative to advanced imaging techniques.</p>

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Conventional preoperative parameters associated with new-onset atrial fibrillation after TAVR: a comparative single-center study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年6月1日

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  • Xiaoqin Tang,
  • Sanjiu Yu,
  • Ruihan Xiao,
  • Chaojun Yan,
  • Yongbo Cheng,
  • Huajie Zheng,
  • Deqing Lin,
  • Xianpu Zhang,
  • Lingfeng Tang,
  • Jun Li,
  • Ping He,
  • Wei Cheng

摘要

Objectives

This study compared conventional preoperative parameters between transcatheter aortic valve replacement (TAVR) patients with and without post-procedural new-onset atrial fibrillation (NOAF) to identify simple risk markers.

Methods

A total of 211 patients undergoing TAVR were enrolled. Post-procedural NOAF occurred in 19 patients (9.0%). Preoperative clinical baseline data, electrocardiographic parameters, conventional echocardiographic indices, laboratory findings, and perioperative variables were compared between the NOAF and No-NOAF groups.

Results

Compared with the No-NOAF group, patients with post-TAVR NOAF were significantly older (P = 0.002) and had a higher heart rate (P = 0.002). Echocardiographically, the NOAF group exhibited larger cardiac dimensions, including right ventricular diameter (P < 0.001), pulmonary artery diameter (P = 0.003), right atrial transverse diameter (P < 0.001), left atrial diameter (P = 0.042), and left ventricular diameter (P = 0.018). Moreover, the NOAF group had lower left ventricular ejection fraction (P = 0.005) and fractional shortening (P = 0.006). Laboratory findings showed significantly higher levels of indirect bilirubin, serum creatinine, uric acid, monocyte percentage, and N-terminal pro-brain natriuretic peptide (NT-proBNP) (P < 0.001), as well as lower glomerular filtration rate and total cholesterol (P = 0.009) in the NOAF group. No significant differences were observed in procedure length, valve type, or intraoperative complications (P > 0.05).

Conclusions

Older age, higher heart rate, enlarged cardiac chambers (including right heart and left atrium), reduced left ventricular systolic function, elevated NT-proBNP, renal dysfunction, higher uric acid, lower total cholesterol, and increased monocyte percentage are associated with post-TAVR NOAF. These easily accessible conventional markers may facilitate early identification of high-risk patients in routine clinical practice, offering a practical alternative to advanced imaging techniques.