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Objective <p>This study was undertaken to examine incidence and predictors of delirium in acute aortic syndrome (AAS) patients with or without surgery, and to evaluate its association with early and follow-up outcomes.</p> Methods <p>A cross-sectional study was retrospectively performed at a single center using a database that was prospectively maintained between 2019 and 2021. Measured outcomes included postoperative results and both early and follow-up survival rates.</p> Results <p>Five hundred ninety-two AAS patients were recruited. Delirium was seen in 31.6% (187/592) of patients. Predictors of delirium included the use of sedatives (odds ratio (OR) = 16.490, 95%-confidence interval (CI) = 8.981–30.279, <i>P</i> &lt; 0.001) and sodium nitroprusside (OR = 2.676, 95%CI = 1.729–4.142, <i>P</i> &lt; 0.001). Delirium was revealed as a risk factor for length of hospital stay (LOS) (OR = 1.101, 95%CI = 1.023–1.185, <i>P</i> &lt; 0.05) and prolonged intensive care unit (ICU) stay (OR = 3.073, 95% CI = 1.744–5.415, <i>P</i> &lt; 0.001).</p> Conclusion <p>The incidence of delirium in AAS patients is 31.6%, significantly increasing LOS and ICU stay duration. The use of sedatives and sodium nitroprusside were revealed as risk factors for delirium.</p>

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Incidence, predictors and outcomes of delirium in acute aortic syndrome

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月5日

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  • Shuying Chen,
  • Yanjun Luo,
  • Xiaojia Lu,
  • Xiansheng Huang,
  • Long Lin,
  • Shaobin Qiu

摘要

Objective

This study was undertaken to examine incidence and predictors of delirium in acute aortic syndrome (AAS) patients with or without surgery, and to evaluate its association with early and follow-up outcomes.

Methods

A cross-sectional study was retrospectively performed at a single center using a database that was prospectively maintained between 2019 and 2021. Measured outcomes included postoperative results and both early and follow-up survival rates.

Results

Five hundred ninety-two AAS patients were recruited. Delirium was seen in 31.6% (187/592) of patients. Predictors of delirium included the use of sedatives (odds ratio (OR) = 16.490, 95%-confidence interval (CI) = 8.981–30.279, P < 0.001) and sodium nitroprusside (OR = 2.676, 95%CI = 1.729–4.142, P < 0.001). Delirium was revealed as a risk factor for length of hospital stay (LOS) (OR = 1.101, 95%CI = 1.023–1.185, P < 0.05) and prolonged intensive care unit (ICU) stay (OR = 3.073, 95% CI = 1.744–5.415, P < 0.001).

Conclusion

The incidence of delirium in AAS patients is 31.6%, significantly increasing LOS and ICU stay duration. The use of sedatives and sodium nitroprusside were revealed as risk factors for delirium.