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Background <p>Total en bloc spondylectomy (TES) was considered aggressive spinal surgery aim to achieved marginal and wide surgical margin in spinal tumor treatment. However, there was limited comparison information between TES and other palliative spinal surgery treatments. This study aimed to report the comparison between TES and Palliative Spinal Surgery (PSS) in terms of clinical and oncologic outcomes.</p> Methods <p>A retrospective cohort study was conducted. The medical records of Spinal Metastasis (SM) treated by a single surgeon were reviewed between January 2014 and December 2020. The propensity score matching was calculated. survivorship, local recurrence, surgical complications, operative blood loss, and time between TES and PSS were reviewed and analyzed.</p> Results <p>A total of 44 patients with a mean age of 56 were included. Twenty-two TES and 22 PSS patients were recruited into the study—no significant difference in demographics data. The TES showed significantly better survival at 6 (<i>p</i> = 0.010) and 12 months (<i>p</i> = 0.020). The local recurrence in the TES group was 4.6% (1 of 22). However, TES showed significantly longer operative time (6&#xa0;h (5.5–6.5) and 3&#xa0;h (2.0-3.5), p-value &lt; 0.001) and more intraoperative blood loss (1150 mL (1000–1800) and 575 mL (350–800), p-value = 0.0002).</p> Conclusions <p>TES showed better survivorship after 6 and 12 months than PSS. The TES also achieved favorable local control of tumors after surgery. Further randomized control of more patients should be conducted to clarify the benefits of TES vis-à-vis metastasis.</p>

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Comparison of outcomes between total en bloc spondylectomy and palliative spinal surgery in metastatic spinal tumor patients: propensity score matching analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月15日

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  • Danaya Yodsuwan,
  • Permsak Paholpak,
  • Taweechok Wisanuyotin,
  • Winai Sirichativapee,
  • Wilasinee Sirichativapee,
  • Weerachai Kosuwon,
  • Tadatsugu Morimoto,
  • Yuichi Kasai,
  • Hideki Murakami

摘要

Background

Total en bloc spondylectomy (TES) was considered aggressive spinal surgery aim to achieved marginal and wide surgical margin in spinal tumor treatment. However, there was limited comparison information between TES and other palliative spinal surgery treatments. This study aimed to report the comparison between TES and Palliative Spinal Surgery (PSS) in terms of clinical and oncologic outcomes.

Methods

A retrospective cohort study was conducted. The medical records of Spinal Metastasis (SM) treated by a single surgeon were reviewed between January 2014 and December 2020. The propensity score matching was calculated. survivorship, local recurrence, surgical complications, operative blood loss, and time between TES and PSS were reviewed and analyzed.

Results

A total of 44 patients with a mean age of 56 were included. Twenty-two TES and 22 PSS patients were recruited into the study—no significant difference in demographics data. The TES showed significantly better survival at 6 (p = 0.010) and 12 months (p = 0.020). The local recurrence in the TES group was 4.6% (1 of 22). However, TES showed significantly longer operative time (6 h (5.5–6.5) and 3 h (2.0-3.5), p-value < 0.001) and more intraoperative blood loss (1150 mL (1000–1800) and 575 mL (350–800), p-value = 0.0002).

Conclusions

TES showed better survivorship after 6 and 12 months than PSS. The TES also achieved favorable local control of tumors after surgery. Further randomized control of more patients should be conducted to clarify the benefits of TES vis-à-vis metastasis.