Scholarlink

<p>Enterovirus 71 (EV71) is a pathogen of concern, especially after its reemergence in most parts of Asia. This virus can lead to severe neurological complications and death, particularly in infants. There are no approved antivirals to prevent or treat EV71 infections, or valid vaccines. EV71 relies on precise virus-host interactions that take place during the viral life cycle, and interference with these offers numerous targets for antiviral strategies that are explored herein. We highlight known antiviral candidates and also alternative avenues to develop novel drugs.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Antiviral candidates for enterovirus 71: targeting viral proteome and stage-specific lifecycle interventions

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月31日

查看全文
  • Jiayi Chen,
  • Tianqi Zhao,
  • Min Ji,
  • Binghui Xia

摘要

Enterovirus 71 (EV71) is a pathogen of concern, especially after its reemergence in most parts of Asia. This virus can lead to severe neurological complications and death, particularly in infants. There are no approved antivirals to prevent or treat EV71 infections, or valid vaccines. EV71 relies on precise virus-host interactions that take place during the viral life cycle, and interference with these offers numerous targets for antiviral strategies that are explored herein. We highlight known antiviral candidates and also alternative avenues to develop novel drugs.