Scholarlink

Objectives <p>Sarcopenia and systemic inflammation are increasingly recognized as contributors to cardiometabolic risk, particularly in clinically vulnerable populations. Handgrip strength (HGS) is a simple, non-invasive marker of muscle function with potential relevance in hospital settings. This study aimed to examine the association between HGS and cardiometabolic indicators—including blood pressure, waist–hip ratio (WHR), visceral adiposity (VA)—and inflammatory markers, specifically erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), among hospitalized adults.</p> Methods <p>A cross-sectional study was conducted among 458 adult inpatients (18–80 years) at Peerless Hospital and B.K. Roy Research Centre, Kolkata, India. HGS was measured using a calibrated dynamometer. Anthropometric parameters, blood pressure, and biochemical markers were recorded. ESR analysis was available for 263 participants and CRP for 109 participants. Sex-stratified analyses were performed. Statistical analysis was conducted using SPSS version 19.0, with significance set at <i>p</i> &lt; 0.05.</p> Results <p>A high prevalence of reduced HGS was observed, with 83% of participants demonstrating weak or very weak grip strength. The most consistent and statistically robust association was found between elevated ESR and reduced HGS (χ² = 108.58, <i>p</i> &lt; 0.001), indicating a strong inflammatory–functional relationship in this hospitalized cohort. Blood pressure showed a significant categorical association with HGS (χ² = 42.55, <i>p</i> &lt; 0.01), though effect estimates were imprecise. Visceral adiposity demonstrated a significant negative association with HGS in males (<i>p</i> &lt; 0.01), while WHR showed a significant correlation in females (<i>p</i> &lt; 0.04). CRP did not demonstrate a statistically significant association.</p> Conclusion <p>In hospitalized adults, systemic inflammation—as reflected by elevated ESR—was the most consistent correlate of reduced handgrip strength. These findings highlight an important inflammatory–functional axis in inpatient care. While cardiometabolic associations were observed, they appear exploratory and require further confirmation. Incorporating HGS assessment into routine hospital evaluation may aid in identifying patients at risk of inflammation-associated functional decline.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Exploring the association between hand grip strength and cardiometabolic health markers in hospitalized adults: a cross-sectional study from Kolkata, India

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年4月19日

查看全文
  • Bijoya Bhattacharjee,
  • Manisha Maity,
  • Subhrojyoti Bhowmick,
  • Abisa Sinha Adhikary,
  • Debkumar Ghosh

摘要

Objectives

Sarcopenia and systemic inflammation are increasingly recognized as contributors to cardiometabolic risk, particularly in clinically vulnerable populations. Handgrip strength (HGS) is a simple, non-invasive marker of muscle function with potential relevance in hospital settings. This study aimed to examine the association between HGS and cardiometabolic indicators—including blood pressure, waist–hip ratio (WHR), visceral adiposity (VA)—and inflammatory markers, specifically erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), among hospitalized adults.

Methods

A cross-sectional study was conducted among 458 adult inpatients (18–80 years) at Peerless Hospital and B.K. Roy Research Centre, Kolkata, India. HGS was measured using a calibrated dynamometer. Anthropometric parameters, blood pressure, and biochemical markers were recorded. ESR analysis was available for 263 participants and CRP for 109 participants. Sex-stratified analyses were performed. Statistical analysis was conducted using SPSS version 19.0, with significance set at p < 0.05.

Results

A high prevalence of reduced HGS was observed, with 83% of participants demonstrating weak or very weak grip strength. The most consistent and statistically robust association was found between elevated ESR and reduced HGS (χ² = 108.58, p < 0.001), indicating a strong inflammatory–functional relationship in this hospitalized cohort. Blood pressure showed a significant categorical association with HGS (χ² = 42.55, p < 0.01), though effect estimates were imprecise. Visceral adiposity demonstrated a significant negative association with HGS in males (p < 0.01), while WHR showed a significant correlation in females (p < 0.04). CRP did not demonstrate a statistically significant association.

Conclusion

In hospitalized adults, systemic inflammation—as reflected by elevated ESR—was the most consistent correlate of reduced handgrip strength. These findings highlight an important inflammatory–functional axis in inpatient care. While cardiometabolic associations were observed, they appear exploratory and require further confirmation. Incorporating HGS assessment into routine hospital evaluation may aid in identifying patients at risk of inflammation-associated functional decline.