Scholarlink

Background and aims <p>Human metapneumovirus (hMPV) is a respiratory virus that can cause upper and lower respiratory disease in people of all ages, especially young children, older adults, and people with weakened immune systems. The hMPV outbreak cases are surging in some countries, including China, India, the UK, Malaysia, and Kazakhstan, during 2024–2025. This outbreak is a concern in the global transition of infectious diseases due to several factors, including an elevated transmission rate, genetic evolution and mutation, incomplete immunity, and severe illness. This review aims to raise concerns about whether the surge of the hMPV virus will turn into another pandemic, what we need to know, and what we should do during this outbreak.</p> Methods <p>We conducted a comprehensive literature search from PubMed, Google Scholar, and Scopus for studies published from database’s inception to June 30, 2025, using human metapneumovirus, genetic mutation, transmission, and prevention of human metapneumovirus as keywords and subsequently extracted relevant information for this review.</p> Results <p>According to recent surveillance data, hMPV cases have significantly increased worldwide, and hospitals have reported a sharp rise in respiratory-related admissions associated with the virus. There are surging hMPV infections nowadays across the globe for several reasons, including “immune debt,” seasonal factors, environmental changes, and agriculture practices such as mixed farming and climate change. Furthermore, no antiviral therapy or vaccine has been developed to combat this challenging respiratory virus. Therefore, preventive measures, awareness-raising, and campaigns have helped fight against the outbreak of hMPV.</p> Conclusion <p>The hMPV outbreak is increasing globally nowadays. Therefore, we need to know about the details of the hMPV virus and its outbreak, including the pattern of the virus, treatment, transmission, and prevention. We should also do the hMPV outbreak by protecting ourselves and others by practicing good hygiene, seeking medical care, and practicing general respiratory illness prevention.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The pathogenicity and potential risk evaluation of human metapneumovirus (hMPV) for global public health

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月5日

查看全文
  • Md. Ismail Tushar,
  • Salsabil Islam,
  • Nuruna Lovely Nishuty,
  • Sadia Islam,
  • Md. Siddiqul Islam,
  • Md. Rabiul Islam

摘要

Background and aims

Human metapneumovirus (hMPV) is a respiratory virus that can cause upper and lower respiratory disease in people of all ages, especially young children, older adults, and people with weakened immune systems. The hMPV outbreak cases are surging in some countries, including China, India, the UK, Malaysia, and Kazakhstan, during 2024–2025. This outbreak is a concern in the global transition of infectious diseases due to several factors, including an elevated transmission rate, genetic evolution and mutation, incomplete immunity, and severe illness. This review aims to raise concerns about whether the surge of the hMPV virus will turn into another pandemic, what we need to know, and what we should do during this outbreak.

Methods

We conducted a comprehensive literature search from PubMed, Google Scholar, and Scopus for studies published from database’s inception to June 30, 2025, using human metapneumovirus, genetic mutation, transmission, and prevention of human metapneumovirus as keywords and subsequently extracted relevant information for this review.

Results

According to recent surveillance data, hMPV cases have significantly increased worldwide, and hospitals have reported a sharp rise in respiratory-related admissions associated with the virus. There are surging hMPV infections nowadays across the globe for several reasons, including “immune debt,” seasonal factors, environmental changes, and agriculture practices such as mixed farming and climate change. Furthermore, no antiviral therapy or vaccine has been developed to combat this challenging respiratory virus. Therefore, preventive measures, awareness-raising, and campaigns have helped fight against the outbreak of hMPV.

Conclusion

The hMPV outbreak is increasing globally nowadays. Therefore, we need to know about the details of the hMPV virus and its outbreak, including the pattern of the virus, treatment, transmission, and prevention. We should also do the hMPV outbreak by protecting ourselves and others by practicing good hygiene, seeking medical care, and practicing general respiratory illness prevention.