Scholarlink

<p>Systemic lupus erythematosus (SLE) in people living with HIV (PLHIV) is rare, with limited prevalence data. We performed symptom-directed antinuclear antibody (ANA) screening in 129 PLHIV, followed by extractable nuclear antigen testing in ANA-positive individuals. SLE was diagnosed using the 2019 ACR–EULAR criteria. ANA positivity was seen in 54 patients, while anti-dsDNA antibodies were detected in four, all diagnosed with SLE. Three patients were male, with polyarthritis as the most common presentation, followed by proteinuria. Sjögren syndrome, dermatomyositis, and primary systemic sclerosis were identified in one patient each. A literature review identified 165 reported cases of HIV-associated SLE, 93 reported between 2014 and 2024.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Antinuclear antibody (ANA) screening based on EULAR/ACR 2019 clinical domain criteria among PLHIV and profile of diagnosed HIV-SLE cases

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月23日

查看全文
  • Jaya Chakravarty,
  • Manaswi Chaubey,
  • Amartya Seth,
  • Thakur Shubh Narayan Rai,
  • Aditya Debuka,
  • Ajay Gupta,
  • P. Raviteja Naidu

摘要

Systemic lupus erythematosus (SLE) in people living with HIV (PLHIV) is rare, with limited prevalence data. We performed symptom-directed antinuclear antibody (ANA) screening in 129 PLHIV, followed by extractable nuclear antigen testing in ANA-positive individuals. SLE was diagnosed using the 2019 ACR–EULAR criteria. ANA positivity was seen in 54 patients, while anti-dsDNA antibodies were detected in four, all diagnosed with SLE. Three patients were male, with polyarthritis as the most common presentation, followed by proteinuria. Sjögren syndrome, dermatomyositis, and primary systemic sclerosis were identified in one patient each. A literature review identified 165 reported cases of HIV-associated SLE, 93 reported between 2014 and 2024.