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<p>Epicutaneo-cava catheters(n-PICC) are widely used in neonates for long-term nutritional support and medication administration, reducing the need for frequent invasive punctures. However, catheter-related thrombosis (CRT) is a serious complication of n-PICC placement. Due to the developmental immaturity of the neonatal coagulation system, neonates are at an increased risk of thrombosis. Currently, there is no standardized protocol for the diagnosis and management of CRT in neonates. This review summarizes the current understanding of risk factors, diagnostic approaches, treatment strategies, and preventive measures for CRT in neonates, aiming to provide clinical guidance.</p>

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Neonatal epicutaneo-cava catheter-related thrombosis: a comprehensive overview

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年6月1日

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  • Xue Jin,
  • Juan Chen

摘要

Epicutaneo-cava catheters(n-PICC) are widely used in neonates for long-term nutritional support and medication administration, reducing the need for frequent invasive punctures. However, catheter-related thrombosis (CRT) is a serious complication of n-PICC placement. Due to the developmental immaturity of the neonatal coagulation system, neonates are at an increased risk of thrombosis. Currently, there is no standardized protocol for the diagnosis and management of CRT in neonates. This review summarizes the current understanding of risk factors, diagnostic approaches, treatment strategies, and preventive measures for CRT in neonates, aiming to provide clinical guidance.