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<p>This study aimed to address the article by Yang et al., titled “<i>Primary giant liposarcoma of the gallbladder: A case report and literature review</i>.” The authors reported an extremely rare case of a large atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) arising in the gallbladder, diagnosed through imaging and histopathological findings. However, due to the tumor’s exceptional size, the positional relationship between the gallbladder and the tumor remains unclear. In such cases, it is essential to histologically analyze the interface between the tumor and the gallbladder. Additionally, imaging revealed both fatty and non-fatty components, necessitating consideration of dedifferentiated liposarcoma as a differential diagnosis. In light of these factors, this study discusses the specific information required for further evaluation and accurate diagnosis.</p>

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Imaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcoma

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月1日

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  • Jiro Ichikawa,
  • Shinji Furuya,
  • Tomonori Kawasaki,
  • Kojiro Onohara,
  • Masanori Wako,
  • Satoshi Ochiai,
  • Tetsuo Hagino,
  • Hirotaka Haro

摘要

This study aimed to address the article by Yang et al., titled “Primary giant liposarcoma of the gallbladder: A case report and literature review.” The authors reported an extremely rare case of a large atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) arising in the gallbladder, diagnosed through imaging and histopathological findings. However, due to the tumor’s exceptional size, the positional relationship between the gallbladder and the tumor remains unclear. In such cases, it is essential to histologically analyze the interface between the tumor and the gallbladder. Additionally, imaging revealed both fatty and non-fatty components, necessitating consideration of dedifferentiated liposarcoma as a differential diagnosis. In light of these factors, this study discusses the specific information required for further evaluation and accurate diagnosis.