Scholarlink

Background <p>Visceral fat has become increasingly recognized as a key modifiable risk factor in the development of heart failure (HF). This study aims to investigate the link between the Metabolic Score for Visceral Fat (METS-VF) and the prevalence of HF, and evaluate whether METS-VF could improve the detection of HF in the general population.</p> Methods <p>24,681 subjects from the 2003–2018 National Health and Nutrition Examination Survey were included in the analysis. HF was determined according to self-reported medical history.</p> Results <p>The overall prevalence of HF was found to be 2.91%. After adjusting for relevant confounders, each one-standard-deviation increase in METS-VF was associated with a 75.4% higher risk of prevalent HF. Participants with METS-VF values in the highest quartile had a 2.731-fold greater risk of prevalent HF than those in the lowest quartile. The relationship between METS-VF and HF appeared nearly linear based on smooth-curve modeling, and subgroup analyses confirmed this association across different demographic groups. When METS-VF was added to standard cardiovascular risk factors, there was a slight improvement in HF discrimination (AUC: 0.867 vs. 0.873, <i>P</i> = 0.003). Reclassification metrics also highlighted the incremental value of including METS-VF.</p> Conclusion <p>The findings of this study demonstrated a strong, linear relationship between METS-VF and the prevalence of HF, suggesting that METS-VF could be an adjunctive tool for improving HF screening in the general population.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Linking metabolic score for visceral fat to heart failure: insights from national health and nutrition examination survey 2003–2018

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月10日

查看全文
  • Daoliang Zhang,
  • Wenrui Shi,
  • Jiakun Liu,
  • Younan Yao,
  • Jian Zhang

摘要

Background

Visceral fat has become increasingly recognized as a key modifiable risk factor in the development of heart failure (HF). This study aims to investigate the link between the Metabolic Score for Visceral Fat (METS-VF) and the prevalence of HF, and evaluate whether METS-VF could improve the detection of HF in the general population.

Methods

24,681 subjects from the 2003–2018 National Health and Nutrition Examination Survey were included in the analysis. HF was determined according to self-reported medical history.

Results

The overall prevalence of HF was found to be 2.91%. After adjusting for relevant confounders, each one-standard-deviation increase in METS-VF was associated with a 75.4% higher risk of prevalent HF. Participants with METS-VF values in the highest quartile had a 2.731-fold greater risk of prevalent HF than those in the lowest quartile. The relationship between METS-VF and HF appeared nearly linear based on smooth-curve modeling, and subgroup analyses confirmed this association across different demographic groups. When METS-VF was added to standard cardiovascular risk factors, there was a slight improvement in HF discrimination (AUC: 0.867 vs. 0.873, P = 0.003). Reclassification metrics also highlighted the incremental value of including METS-VF.

Conclusion

The findings of this study demonstrated a strong, linear relationship between METS-VF and the prevalence of HF, suggesting that METS-VF could be an adjunctive tool for improving HF screening in the general population.