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Background <p>National surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and middle-income countries. Here we employ data from the World Mental Health surveys to characterize the onset, course, severity, and treatment of OCD across a range of countries in different geographic regions of the world.</p> Methods <p>Data came from general population surveys carried out in 10 countries (Argentina, Australia, Colombia, Iraq, Poland, People’s Republic of China, Portugal, Romania, Saudi Arabia, Spain) using a consistent research protocol and interview. A total of 26,136 adults were assessed for OCD in face-to-face interviews and were included in the present analyses. We examined lifetime and 12-month prevalence as well as age of onset, persistence, severity, and treatment of <i>DSM-IV</i> OCD in six high-income countries (HICs) and four low- or middle-income countries (LMICs). We also investigated socio-demographic variables and temporally prior mental disorders as predictors of OCD onset, persistence, severity, and treatment.</p> Results <p>Across the 10 countries surveyed, OCD has a combined lifetime prevalence of 4.1%. The 12-month prevalence (3.0%) is nearly as high, suggesting a highly persistent course of illness. Age of onset is early, with more than 80% of OCD cases beginning by early adulthood. Most OCD cases in the community are mild (47.0%) or very mild (27.5%), with a smaller percentage designated as moderate (22.9%) or severe (2.7%) by the Yale-Brown Obsessive-Compulsive Scale. Only 19.8% of respondents with OCD received any mental health treatment in the past year, with treatment rates much higher in HICs (40.5%) than LMICs (7.0%). Cross-nationally, OCD commonly emerges in adolescence or early adulthood against a backdrop of earlier-occurring mental disorders. With few exceptions (e.g., prior social phobia), the socio-demographic and psychopathological risk factors for OCD onset, persistence, severity, and treatment are distinct.</p> Conclusions <p>These cross-national data underscore clinical lessons regarding the importance of early diagnosis of OCD and comprehensive evaluation of comorbidity; draw attention to OCD as an undertreated disorder, particularly in LMIC contexts; and emphasize the public health significance of this often-overlooked condition.</p>

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Obsessive-compulsive disorder in the World Mental Health surveys

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月9日

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  • Dan J. Stein,
  • Ayelet Meron Ruscio,
  • Yasmin Altwaijri,
  • Wai Tat Chiu,
  • Nancy A. Sampson,
  • Sergio Aguilar-Gaxiola,
  • Ali Al-Hamzawi,
  • Jordi Alonso,
  • Stephanie Chardoul,
  • Oye Gureje,
  • Chiyi Hu,
  • Elie G. Karam,
  • John J. McGrath,
  • Fernando Navarro-Mateu,
  • Kate M. Scott,
  • Juan Carlos Stagnaro,
  • Yolanda Torres,
  • Cristian Vladescu,
  • Jacek Wciórka,
  • Miguel Xavier,
  • Ronald C. Kessler,
  • Yasmin A. Altwaijri,
  • Laura Helena Andrade,
  • Lukoye Atwoli,
  • Corina Benjet,
  • Guilherme Borges,
  • Ronny Bruffaerts,
  • Brendan Bunting,
  • Jose Miguel Caldas-de-Almeida,
  • Graça Cardoso,
  • Louisa Degenhardt,
  • Giovanni de Girolamo,
  • Josep Maria Haro,
  • Meredith G. Harris,
  • Hristo Hinkov,
  • Chiyi Hu,
  • Peter de Jonge,
  • Aimee Nasser Karam,
  • Georges Karam,
  • Alan E. Kazdin,
  • Norito Kawakami,
  • Andrzej Kiejna,
  • Viviane Kovess-Masfety,
  • Maria Elena Medina-Mora,
  • Jacek Moskalewicz,
  • Daisuke Nishi,
  • Marina Piazza,
  • José Posada-Villa,
  • Annelieke Roest,
  • Margreet ten Have,
  • Nathan Tintle,
  • Maria Carmen Viana,
  • Daniel V. Vigo,
  • David R. Williams,
  • Bogdan Wojtyniak,
  • Alan M. Zaslavsky

摘要

Background

National surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and middle-income countries. Here we employ data from the World Mental Health surveys to characterize the onset, course, severity, and treatment of OCD across a range of countries in different geographic regions of the world.

Methods

Data came from general population surveys carried out in 10 countries (Argentina, Australia, Colombia, Iraq, Poland, People’s Republic of China, Portugal, Romania, Saudi Arabia, Spain) using a consistent research protocol and interview. A total of 26,136 adults were assessed for OCD in face-to-face interviews and were included in the present analyses. We examined lifetime and 12-month prevalence as well as age of onset, persistence, severity, and treatment of DSM-IV OCD in six high-income countries (HICs) and four low- or middle-income countries (LMICs). We also investigated socio-demographic variables and temporally prior mental disorders as predictors of OCD onset, persistence, severity, and treatment.

Results

Across the 10 countries surveyed, OCD has a combined lifetime prevalence of 4.1%. The 12-month prevalence (3.0%) is nearly as high, suggesting a highly persistent course of illness. Age of onset is early, with more than 80% of OCD cases beginning by early adulthood. Most OCD cases in the community are mild (47.0%) or very mild (27.5%), with a smaller percentage designated as moderate (22.9%) or severe (2.7%) by the Yale-Brown Obsessive-Compulsive Scale. Only 19.8% of respondents with OCD received any mental health treatment in the past year, with treatment rates much higher in HICs (40.5%) than LMICs (7.0%). Cross-nationally, OCD commonly emerges in adolescence or early adulthood against a backdrop of earlier-occurring mental disorders. With few exceptions (e.g., prior social phobia), the socio-demographic and psychopathological risk factors for OCD onset, persistence, severity, and treatment are distinct.

Conclusions

These cross-national data underscore clinical lessons regarding the importance of early diagnosis of OCD and comprehensive evaluation of comorbidity; draw attention to OCD as an undertreated disorder, particularly in LMIC contexts; and emphasize the public health significance of this often-overlooked condition.