Recent cervical cancer incidence, stage at diagnosis, and mortality trends in Puerto Rico, 2001–2019

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2024年8月13日

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Ana P. Ortiz,
Carlos R. Torres-Cintrón,
Eduardo J. Santiago-Rodríguez,
Jeslie M. Ramos-Cartagena,
Tonatiuh Suárez-Ramos,
Haluk Damgacioglu,
Vivian Colón-López,
Karen J. Ortiz-Ortiz,
Ashish A. Deshmukh

摘要

Background

Cervical cancer incidence is rising in Puerto Rico (PR). Whether the increase is real or reflective of increased diagnostic scrutiny remains unclear.

Methods

Using data from the PR Central Cancer Registry for 2001–2019, we estimated trends of hysterectomy-corrected cervical cancer incidence and mortality rates, overall, and by stage at diagnosis and age.

Results

Overall, cervical cancer incidence (per 100,000) increased 1.6%/year (95% CI, -0.5% to 3.8%) from 12.5 to 15.3, with a prominent increase in distant-stage disease (4.5%/year [95% CI, 1.6% to 8.0%]), particularly among screening age eligible (25–64-year-old) women (5.8%/year [95% CI, 2.1% to 10.6%]). Mortality rates in this age-group remained stable during the study period.

Conclusions

Increased occurrence of distant-stage disease among screening-eligible women is troubling and may reflect a real increase. Future research is needed to elucidate the factors underlying these trends. Improved prevention is also an urgent priority to reverse the rising cervical cancer incidence in PR.