Aim <p>Early mobilization (EM) is essential for an Enhanced Recovery After Surgery (ERAS) program. This study aimed to develop and evaluate a specific early postoperative mobilization program for grade IV day surgery patients.</p> Methods <p>Patients who underwent grade IV surgery at our center between January and October 2022 were divided into a control group (<i>N</i> = 96) and an experimental group (<i>N</i> = 95) using random digitization. The control group followed the standard rehabilitation guidelines, whereas the experimental group adhered to a quantitative rehabilitation approach. We compared outcomes such as time to first-in-bed and out-of-bed activities, pain scores at 6&#xa0;h post-surgery, and at discharge, and overall satisfaction.</p> Results <p>The time to first postoperative in-bed activity and time to first postoperative out-of-bed activity in the experimental group was significantly shorter than that in the control group (<i>P</i> &lt; 0.05). The pain scores at 6&#xa0;h postoperatively and before discharge were also significantly lower in the experimental group, with statistically significant differences (<i>P</i> &lt; 0.05). No significant differences were observed in adverse events, emotional states, or overall satisfaction.</p> Conclusion <p>Quantitative rehabilitation guidance enhanced early recovery compared with standard protocols and maintained similar safety levels, proving to be an effective method for day surgery patients.</p> Trial registration <p>This study passed review by the Chinese Clinical Trial Registry (Registration No. ChiCTR2400090566) and registration date is October 8th, 2024 (<a href="https://www.chictr.org.cn/">https://www.chictr.org.cn/</a>).</p>