Background <p>Increasing donor consent rates in countries with low post-mortem donation rates such as Türkiye is paramount. This study explores the experiences of donor relatives in Türkiye who approved post mortem organ donation after brain death, aiming to identify emotional, cognitive, and ethical factors influencing their decisions and post-decision experiences, to inform strategies for increasing consent rates in developing countries.</p> Methods <p>This qualitative study involved semi-structured interviews with eight donor relatives who consented to organ donation, and data were analysed using thematic analysis.</p> Results <p>Two main fields were identified: (1) Factors influencing the donation decision, with themes: (a) decision-related factors, (b) health system factors, and (c) individual factors; and (2) post-decision experiences, with themes: (a) satisfaction with the decision, (b) curiosity about the recipient, (c) meaning of donation, and (d) creating donation awareness.</p> Conclusion <p>Empathic motivations, previously stated wishes, the attitude of healthcare professionals, and understanding brain death influence the decisions of donors’ relatives. Trust in healthcare professionals helps reduce ethical uncertainty, contributing to a more confident and informed decision-making process. The study found that concerns during the decision-making process and uncertainties such as ‘What will happen next?’ were replaced by spiritual satisfaction and contentment after the decision. The research results provide evidence-based insights into the organ donation decision-making process and offer recommendations for improving public perception and increasing consent rates.</p>