Introduction <p>The accuracy of ultrasound diagnosis of nurses in intensive care unit is helpful to improve the quality of nursing care. The traditional ultrasound teaching model has been unable to meet the needs of intensive care. Ultrasound simulation training as a new teaching model can improve the quality and efficiency of teaching. Therefore, the application of ultrasonic simulation training in intensive care ultrasound teaching hopes to improve the technical expertise, proficiency and accuracy of ultrasound use in intensive care nurses.</p> Methods <p>A total of 40 nurses were divided equally into two groups. Twenty nurses in the control group were taught with the classic teaching method, and 20 nurses in the experimental group were taught with the ultrasound simulation training method. Each nurse practiced for about 15&#xa0;min each time, three times a week, for a total of 30 days. After training, the theoretical and practical scores of the two groups were compared.</p> Result <p>The experimental group were significantly higher than those of the control group, and the difference was statistically significant (<i>p</i> &lt; 0.05) including the aspect of the theoretical scores (<i>p</i> &lt; 0.001), practical scores (<i>p</i> &lt; 0.001), and nursing satisfaction rates (<i>p</i> &lt; 0.05).</p> Conclusions <p>Compared with traditional teaching mode, ultrasonic simulation training is helpful to improve the teaching quality of intensive care nursing, and it can be tried to be applied to ultrasonic training in the future.</p>