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Objective <p>Uterine artery embolization (UAE) for fibroids may cause ovarian dysfunction, particularly concerning for reproductive-aged women. This study evaluated whether a structured telemedicine follow-up protocol enhances timely identification of early-stage ovarian dysfunction compared to traditional outpatient care, thereby expanding the therapeutic intervention window.</p> Methods <p>This retrospective cohort study analyzed 232 women aged 18–40 who underwent UAE at Fujian Maternity and Child Health Hospital (December 2020–2023). Participants were assigned to WeChat telemedicine platform (<i>n</i> = 138) or traditional follow-up (<i>n</i> = 94). Primary outcome was early identification of ovarian dysfunction, defined as diminished ovarian reserve (AMH &lt; 1.1&#xa0;ng/ml, FSH 10-15&#xa0;IU/L), or subclinical POI (FSH 15-25&#xa0;IU/L). Secondary outcomes included hormone replacement therapy adherence and quality of life scores.</p> Results <p>Telemedicine significantly improved early detection of ovarian dysfunction (21% vs 3%, <i>p</i> &lt; 0.001), particularly in women aged 28–36 (OR = 7.84, 95%CI: 1.05–58.44). Follow-up completion increased substantially (3.83 ± 0.60 vs 2.67 ± 1.04 visits, <i>p</i> &lt; 0.001). Among patients with confirmed dysfunction, telemedicine achieved superior hormone therapy adherence (82.8% vs 27.3% good adherence, <i>p</i> &lt; 0.001) and better quality of life scores at 3&#xa0;months (MENQOL: 49.83 ± 10.82 vs 59.09 ± 15.30, <i>p</i> = 0.038).</p> Conclusion <p>Telemedicine follow-up after UAE significantly is significantly associated with early detection of ovarian dysfunction and treatment adherence. Integration of structured remote monitoring protocols into post-UAE care pathways may improve long-term reproductive health outcomes.</p>

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Telemedicine follow-up improves early detection of ovarian dysfunction after uterine artery embolization: a retrospective cohort study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月22日

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  • Weixi Zheng,
  • Zhihao Fang,
  • Tianhong Cai,
  • Rong Zhang,
  • Nating Wang,
  • Rong Chen,
  • Bing Lin,
  • Jinxia Nian

摘要

Objective

Uterine artery embolization (UAE) for fibroids may cause ovarian dysfunction, particularly concerning for reproductive-aged women. This study evaluated whether a structured telemedicine follow-up protocol enhances timely identification of early-stage ovarian dysfunction compared to traditional outpatient care, thereby expanding the therapeutic intervention window.

Methods

This retrospective cohort study analyzed 232 women aged 18–40 who underwent UAE at Fujian Maternity and Child Health Hospital (December 2020–2023). Participants were assigned to WeChat telemedicine platform (n = 138) or traditional follow-up (n = 94). Primary outcome was early identification of ovarian dysfunction, defined as diminished ovarian reserve (AMH < 1.1 ng/ml, FSH 10-15 IU/L), or subclinical POI (FSH 15-25 IU/L). Secondary outcomes included hormone replacement therapy adherence and quality of life scores.

Results

Telemedicine significantly improved early detection of ovarian dysfunction (21% vs 3%, p < 0.001), particularly in women aged 28–36 (OR = 7.84, 95%CI: 1.05–58.44). Follow-up completion increased substantially (3.83 ± 0.60 vs 2.67 ± 1.04 visits, p < 0.001). Among patients with confirmed dysfunction, telemedicine achieved superior hormone therapy adherence (82.8% vs 27.3% good adherence, p < 0.001) and better quality of life scores at 3 months (MENQOL: 49.83 ± 10.82 vs 59.09 ± 15.30, p = 0.038).

Conclusion

Telemedicine follow-up after UAE significantly is significantly associated with early detection of ovarian dysfunction and treatment adherence. Integration of structured remote monitoring protocols into post-UAE care pathways may improve long-term reproductive health outcomes.