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Introduction <p>Since 2017, Burkina Faso has rolled out a plan to eliminate vertical transmission of HIV (eMTCT). Elimination will only be achieved when mothers have regular follow-up and good compliance with antiretroviral therapy (ART). The aim of this article is to study the incidence and associated factors for loss to follow-up (LTFU ), in women living with HIV (WLHIV) monitored as part of the eMTCT.</p> Methods <p>This study consisted of a retrospective analysis of routinely collected data from pregnant women who were screened and initiated ART in the Do and Dafra health districts of Bobo-Dioulasso between 2017 and 2020 as part of the eMTCT. The study ran from May 2023 to March 2024. The Kaplan-Meier model was used to estimate the rate of LTFU; the Cox model was used for identification of factors associated with LTFU and verification of Kaplan-Meier results.</p> Results <p>Three hundred and four newly diagnosed pregnant WLHIV were included in this study. The median age of the mothers was 30 [24; 36] years. The incidence of LTFU was 22.9 per 100 person-years. Younger age (HR = 2.40; 95%CI: 1.37–4.20) was associated with a higher incidence of LTFU, whereas urban residence (HR = 0.57; 95%CI: 0.39–0.85), in contrast to rural residence, was associated with a lower incidence of LTFU.</p> Conclusion <p>The study showed a high incidence of LTFU, associated with younger age and rural residence, in the eMTCT programme in Burkina Faso.</p>

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Incidence of loss to follow-up and associated factors among mothers on antiretroviral therapy in the context of elimination of mother-to-child transmission of HIV in two health districts of Bobo-Dioulasso in Burkina Faso

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  • 发表日期：

    2025年3月29日

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  • Béninwendé Léticia Delphine Sakana,
  • Ziemlé Clément Meda,
  • Bernard Ilboudo,
  • Abdoulaye Ouattara,
  • Blahima Konate,
  • Bernard Eric Dabone,
  • Manitu Serge Mayaka,
  • Gueswendé Léon Savadogo,
  • Philippe Van De Perre

摘要

Introduction

Since 2017, Burkina Faso has rolled out a plan to eliminate vertical transmission of HIV (eMTCT). Elimination will only be achieved when mothers have regular follow-up and good compliance with antiretroviral therapy (ART). The aim of this article is to study the incidence and associated factors for loss to follow-up (LTFU ), in women living with HIV (WLHIV) monitored as part of the eMTCT.

Methods

This study consisted of a retrospective analysis of routinely collected data from pregnant women who were screened and initiated ART in the Do and Dafra health districts of Bobo-Dioulasso between 2017 and 2020 as part of the eMTCT. The study ran from May 2023 to March 2024. The Kaplan-Meier model was used to estimate the rate of LTFU; the Cox model was used for identification of factors associated with LTFU and verification of Kaplan-Meier results.

Results

Three hundred and four newly diagnosed pregnant WLHIV were included in this study. The median age of the mothers was 30 [24; 36] years. The incidence of LTFU was 22.9 per 100 person-years. Younger age (HR = 2.40; 95%CI: 1.37–4.20) was associated with a higher incidence of LTFU, whereas urban residence (HR = 0.57; 95%CI: 0.39–0.85), in contrast to rural residence, was associated with a lower incidence of LTFU.

Conclusion

The study showed a high incidence of LTFU, associated with younger age and rural residence, in the eMTCT programme in Burkina Faso.