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Objective <p>This study investigates the association between A Body Shape Index (ABSI) and risk of benign prostatic hyperplasia (BPH) in middle-aged and older men.</p> Methods <p>Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS), including 3,223 men aged ≥ 45 years. ABSI was calculated from waist circumference, BMI, and height. Logistic regression and restricted cubic spline models were used to assess the association and potential nonlinear relationship between ABSI and incident BPH.</p> Results <p>During 4 years of follow-up, 260 new BPH cases were identified. A nonlinear association was observed: ABSI was significantly associated with increased BPH risk within a moderate range (7.420–8.916), but not at lower or higher ABSI levels (OR = 1.532, 95% CI: 1.015–2.314, <i>p</i> = 0.042).</p> Conclusion <p>ABSI was associated with BPH risk in a nonlinear pattern. These findings suggest that ABSI may serve as a potential risk indicator, although further research is needed. Limitations include reliance on self-reported BPH diagnosis and lack of biomarker data.</p>

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The relationship between the a body shape index and benign prostatic hyperplasia in middle-aged and elderly adults: a nationwide cohort study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年12月23日

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  • Bing Li,
  • Zhiqiang Zhang,
  • Junping Li,
  • Xiaoqiang Liu

摘要

Objective

This study investigates the association between A Body Shape Index (ABSI) and risk of benign prostatic hyperplasia (BPH) in middle-aged and older men.

Methods

Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS), including 3,223 men aged ≥ 45 years. ABSI was calculated from waist circumference, BMI, and height. Logistic regression and restricted cubic spline models were used to assess the association and potential nonlinear relationship between ABSI and incident BPH.

Results

During 4 years of follow-up, 260 new BPH cases were identified. A nonlinear association was observed: ABSI was significantly associated with increased BPH risk within a moderate range (7.420–8.916), but not at lower or higher ABSI levels (OR = 1.532, 95% CI: 1.015–2.314, p = 0.042).

Conclusion

ABSI was associated with BPH risk in a nonlinear pattern. These findings suggest that ABSI may serve as a potential risk indicator, although further research is needed. Limitations include reliance on self-reported BPH diagnosis and lack of biomarker data.