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<p>Multiple symmetric lipomatosis (MSL), or Madelung disease, is a rare disorder characterized by symmetrical, non-encapsulated adipose tissue deposition, predominantly involving the neck and upper trunk. It is strongly associated with chronic alcohol consumption.</p><p>We report a 33-year-old male with a history of regular alcohol intake presenting with a progressively enlarging cervical mass. Imaging revealed bilateral, symmetrical lipomatous deposits consistent with MSL. The patient underwent surgical excision under general anesthesia with satisfactory cosmetic and functional outcomes.</p><p>This report highlights the clinical presentation, diagnostic approach, and management of MSL, emphasizing the importance of early recognition. A short-term follow-up showed no recurrence; however, long-term surveillance and alcohol cessation remain essential to reduce recurrence risk.</p>

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Multiple symmetric lipomatosis (Madelung disease) presenting as cervical lipomatous mass in a middle-aged male with alcohol use in Nepal: A Case Report

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  • 发表日期：

    2026年5月2日

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  • Suzita Hirachan,
  • Adheesh Bhandari

摘要

Multiple symmetric lipomatosis (MSL), or Madelung disease, is a rare disorder characterized by symmetrical, non-encapsulated adipose tissue deposition, predominantly involving the neck and upper trunk. It is strongly associated with chronic alcohol consumption.

We report a 33-year-old male with a history of regular alcohol intake presenting with a progressively enlarging cervical mass. Imaging revealed bilateral, symmetrical lipomatous deposits consistent with MSL. The patient underwent surgical excision under general anesthesia with satisfactory cosmetic and functional outcomes.

This report highlights the clinical presentation, diagnostic approach, and management of MSL, emphasizing the importance of early recognition. A short-term follow-up showed no recurrence; however, long-term surveillance and alcohol cessation remain essential to reduce recurrence risk.