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Objective <p>To retrospectively analyze the repair of seven cases of complicated pharyngocutaneous fistula (PCF) to provide a reference for the treatment of complicated PCF.</p> Methods <p>We retrospectively analyzed the clinical data of seven patients with complicated PCF from February 2017 to December 2021, including six males and one female, with a history of neck radiotherapy in two cases. The range of PCF mucosal defects was 1.0&#xa0;cm × 2.0–5.0&#xa0;cm × 7.0&#xa0;cm. A pedicled flap or free flap was chosen for repair depending on the site and size of the defect. A total of eight flaps were used to repair complicated PCF defects.</p> Results <p>One of the seven patients healed after conservative treatment. Among the five patients who underwent pedicled flap repair, three had first-intention healing, one had second-intention healing, and one had tumor recurrence with unhealed PCF. Free flap repair was performed in one case, which had first-intention healing.</p> Conclusion <p>Early, prompt, and appropriate treatment can prevent a PCF from progressing to complicated PCF. The repair of the complicated PCF needs to be individualized according to the patient’s local defect and the surgeon’s clinical experience.</p>

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Complicated pharyngocutaneous fistula repair after head and neck cancer surgery: a case series of 7 patients

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月9日

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  • Weihua Zhou,
  • Huajun Feng,
  • Sai Liang,
  • Shengen Xu,
  • Zhuoping Liang,
  • Yuanyuan Wang,
  • Gang Qin

摘要

Objective

To retrospectively analyze the repair of seven cases of complicated pharyngocutaneous fistula (PCF) to provide a reference for the treatment of complicated PCF.

Methods

We retrospectively analyzed the clinical data of seven patients with complicated PCF from February 2017 to December 2021, including six males and one female, with a history of neck radiotherapy in two cases. The range of PCF mucosal defects was 1.0 cm × 2.0–5.0 cm × 7.0 cm. A pedicled flap or free flap was chosen for repair depending on the site and size of the defect. A total of eight flaps were used to repair complicated PCF defects.

Results

One of the seven patients healed after conservative treatment. Among the five patients who underwent pedicled flap repair, three had first-intention healing, one had second-intention healing, and one had tumor recurrence with unhealed PCF. Free flap repair was performed in one case, which had first-intention healing.

Conclusion

Early, prompt, and appropriate treatment can prevent a PCF from progressing to complicated PCF. The repair of the complicated PCF needs to be individualized according to the patient’s local defect and the surgeon’s clinical experience.