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Background <p>Abdominal re-operation, or relaparotomy, refers to any repeat surgical intervention performed for intra-abdominal or wound complications during the same hospital admission or within 60 days of the initial operation. However, the regional level of relaparotomy remains unknown in East Africa. Hence, the objective of this systematic review and meta-analysis was to estimate the prevalence of relaparotomy and its associated factors in East Africa.</p> Methods <p>Studies were accessed through an electronic web-based search strategy from PubMed, Cochrane Library, Google Scholar, Embase, PsycINFO, and CINAHL by using a combination of search terms. The quality of each included article was assessed using criteria adapted from the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI). All statistical analyses were done using STATA version 17 software for windows, and meta-analysis was carried out using a random-effects method. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed for reporting results.</p> Results <p>The overall prevalence of relaparotomy was determined to be 17.36% (95% CI: 7.03–27.68; I² = 99.89%). Patients OR latency of &gt; 60&#xa0;h was 2.33 times more likely to undergo re-laparotomy compared with patients operated in &lt; 60&#xa0;h (AOR = 2.33 (95%CI [1.22–3.45)). Patients with anastomotic leak were 2 times more likely to undergo re-laparotomy compared to patients without leak (AOR = 2 (95%CI [1.35–2.64)). Older patients were 4.13 times more likely to undergo re-laparotomy compared to young patients (AOR = 4.13 (95%CI [-4.62–12.89)).</p> Conclusion <p>This meta-analysis provides valuable insights into the prevalence and associated factors of relaparotomy, highlighting key regional variations and patient characteristics. The study identified several factors influencing the prevalence of relaparotomy, including the duration of illness, low systolic blood pressure, anastomotic leaks, delayed surgical intervention, and age. </p>

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Prevalence and determinants of relaparotomy in East African healthcare institutions: a systematic review and meta-analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月9日

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  • Henok Biresaw Netsere,
  • Yihun Miskir,
  • Alemshet Yirga Berhie,
  • Abebeu Tegenaw Delie,
  • Mekedes Misiganaw Dagnaw,
  • Daniel Mekete Alemu,
  • Alemayehu Anley,
  • Abdurehman Ayele,
  • Birhanu Ayenew,
  • Asnake Gashaw Belayneh

摘要

Background

Abdominal re-operation, or relaparotomy, refers to any repeat surgical intervention performed for intra-abdominal or wound complications during the same hospital admission or within 60 days of the initial operation. However, the regional level of relaparotomy remains unknown in East Africa. Hence, the objective of this systematic review and meta-analysis was to estimate the prevalence of relaparotomy and its associated factors in East Africa.

Methods

Studies were accessed through an electronic web-based search strategy from PubMed, Cochrane Library, Google Scholar, Embase, PsycINFO, and CINAHL by using a combination of search terms. The quality of each included article was assessed using criteria adapted from the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI). All statistical analyses were done using STATA version 17 software for windows, and meta-analysis was carried out using a random-effects method. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed for reporting results.

Results

The overall prevalence of relaparotomy was determined to be 17.36% (95% CI: 7.03–27.68; I² = 99.89%). Patients OR latency of > 60 h was 2.33 times more likely to undergo re-laparotomy compared with patients operated in < 60 h (AOR = 2.33 (95%CI [1.22–3.45)). Patients with anastomotic leak were 2 times more likely to undergo re-laparotomy compared to patients without leak (AOR = 2 (95%CI [1.35–2.64)). Older patients were 4.13 times more likely to undergo re-laparotomy compared to young patients (AOR = 4.13 (95%CI [-4.62–12.89)).

Conclusion

This meta-analysis provides valuable insights into the prevalence and associated factors of relaparotomy, highlighting key regional variations and patient characteristics. The study identified several factors influencing the prevalence of relaparotomy, including the duration of illness, low systolic blood pressure, anastomotic leaks, delayed surgical intervention, and age.