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Objective <p>To investigate the frailty status and associated risk factors in older patients diagnosed with interstitial lung disease (ILD).</p> Methods <p>A total of 242 older ILD patients admitted to the hospital between April 2023 and April 2024 were recruited using a cluster sampling method. Comprehensive clinical data were collected, including information from the General Data Questionnaire, the Fried Frailty Phenotype (FFP) Scale, the Dyspnea Scale, the Hospital Anxiety and Depression Scale, the Pittsburgh Sleep Quality Index, and the Self-Efficacy for Managing Chronic Disease Scale. Based on the Fried criteria, participants were categorized into two groups: the frailty group (FFP ≥ 3) and the non-frailty group (FFP &lt; 3). </p> Results <p>The prevalence of frailty among older patients with ILD was found to be 38.02%. Multivariate analysis revealed that age (OR = 1.064), polypharmacy (OR = 2.479), poor sleep quality (OR = 5.687), and dyspnea (OR = 10.316) were independent risk factors for frailty (P &lt; 0.05). </p> Conclusions <p>Frailty in older patients with ILD is significantly associated with age, polypharmacy, poor sleep quality, and dyspnea. Healthcare professionals, particularly nursing staff, should closely monitor frailty indicators in this population and implement timely, targeted interventions to mitigate its development and progression.</p>

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Analysis of risk factors for frailty in older inpatients with interstitial lung disease

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月13日

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  • Yan Chen,
  • Xuemei Zhu,
  • Jing Wei,
  • Xiaoyun Gu,
  • Jiaying Fei,
  • Qiong Liu

摘要

Objective

To investigate the frailty status and associated risk factors in older patients diagnosed with interstitial lung disease (ILD).

Methods

A total of 242 older ILD patients admitted to the hospital between April 2023 and April 2024 were recruited using a cluster sampling method. Comprehensive clinical data were collected, including information from the General Data Questionnaire, the Fried Frailty Phenotype (FFP) Scale, the Dyspnea Scale, the Hospital Anxiety and Depression Scale, the Pittsburgh Sleep Quality Index, and the Self-Efficacy for Managing Chronic Disease Scale. Based on the Fried criteria, participants were categorized into two groups: the frailty group (FFP ≥ 3) and the non-frailty group (FFP < 3).

Results

The prevalence of frailty among older patients with ILD was found to be 38.02%. Multivariate analysis revealed that age (OR = 1.064), polypharmacy (OR = 2.479), poor sleep quality (OR = 5.687), and dyspnea (OR = 10.316) were independent risk factors for frailty (P < 0.05).

Conclusions

Frailty in older patients with ILD is significantly associated with age, polypharmacy, poor sleep quality, and dyspnea. Healthcare professionals, particularly nursing staff, should closely monitor frailty indicators in this population and implement timely, targeted interventions to mitigate its development and progression.