Background <p>Loneliness is a key driver of health inequities faced by autistic children. However, research on how parent-led organizations align their goals to address loneliness remains scarce.</p> Methods <p>Between 2021 and 2024, a qualitative study was conducted in three Chinese cities, utilizing semi-structured interviews with 37 stakeholders and participatory observations.</p> Results <p>Parent-led organizational interventions exhibited three interrelated goals: shifting from individual family-based strategies (exemplified by but not limited to ‘having a second child for companionship’) to collective ‘outings for social interaction outside the home’ (with peer companionship programs as organizational alternatives); avoiding the stigma of loneliness by framing interventions as social integration, which obscures links between loneliness and health; and prioritizing parents’ social reintegration over autistic children’s loneliness needs. Limitations of these intervention goals, potentially weakening intervention efficacy and failing to create conditions conducive to reducing loneliness-related health disparities, are shaped by China’s social transformation: collectivist values emphasize interdependence, driving demand for integration; limited formal welfare pushes parents to organize; and stigma around autism discourages explicit discussion of loneliness.</p> Conclusions <p>This study highlights the uniqueness of China’s parent-led intervention model—characterized by cultural adaptation, stigma mitigation, and dual support for both autistic children and parents—compared to Western models that focus more on professionalized services. While parent-led organizations fill essential gaps through culturally grounded, peer-supported pathways that formal services often cannot reach, distinguishing between social and emotional loneliness and centering autistic children’s heterogeneous needs are critical to refining these interventions and fostering meaningful belonging.</p>