The role of natural outdoor environment on COVID-19 mortality and hospitalisations among older community-dwellers in the pre-vaccination period: the Register RELOC-AGE cohort study in Sweden
摘要
Most COVID-19-related deaths and hospitalisations occurred among older people. Natural outdoor environments influence health outcomes, but the evidence of their effect on COVID-19 outcomes among older adults is limited. This study aimed to investigate associations between residential natural outdoor environment and COVID-19-related deaths or hospitalisations among community dwellers aged 59 years or older, and whether income and education moderated these associations.
MethodsThe current study is part of the Register RELCOC-AGE cohort and included ≥ 59-year-old community-dwellers (N = 299,219) in Scania, Sweden. The main exposure was the Perceived Sensory Dimension Score (PSD-score), an aggregated area-level score indicating the presence of residential natural outdoor environment, measured between 2008 and 2019, grouped into low, intermediate, and high PSD-score. COVID-19 deaths and hospitalisations were assessed from 1 January to 31 December 2020. Hazard ratios (HRs) were estimated using Cox proportional hazard regression, and moderation by income or education was assessed using interaction terms. Models were adjusted for demographic and socioeconomic characteristics, population density and comorbidities.
ResultsThe adjusted HRs for COVID-19 deaths and hospitalisations among intermediate– as compared to low PSD-score residents– were 0.90 (95% CI: 0.71–1.15) and 0.88 (95% CI: 0.77–1.01), respectively. Among high PSD-score residents, adjusted HRs were 0.88 (95% CI: 0.62–1.24) and 0.92 (95% CI: 0.76–1.12) for COVID-19 deaths and hospitalisations, respectively. No evidence of moderation of associations by income and education was found.
ConclusionA protective effect from residential natural outdoor environment on COVID-19 hospitalisation and death was suggested, but statistical uncertainty was substantial and the evidence thus inconclusive. Future investigations across diverse populations could shed more light on the role of residential living environments in mitigating the consequences of epidemics and pandemics.