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Background <p>Kazakhstan’s healthcare system and population health have changed significantly between 2014 and 2022, especially due to the COVID-19 pandemic. This study analyzes mortality trends during this period to better understand the health challenges and regional differences that have emerged, addressing a gap in comprehensive research.</p> Methods <p>We analyzed mortality data from Kazakhstan’s Unified National Electronic Health System (2014–2022), calculating age-standardized mortality rates and years of life lost. Regional trends were assessed using linear regression.</p> Results <p>Overall mortality increased from 550.84 to 678.37 per 100,000 between 2014–2022, with significant regional variations. “Other disorders of the brain” emerged as a leading cause of premature mortality. COVID-19 significantly disrupted mortality patterns in 2020–2021. Mortality rates were consistently higher in males across most age groups, with a sharp increase after age 55, while “other disorders of the brain” emerged as a leading cause of premature mortality.</p> Conclusions <p>Kazakhstan faces evolving mortality challenges, with stark regional disparities and a concerning rise in neurological disorders. These findings underscore the need for targeted public health interventions and improved cause-of-death reporting.</p>

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Mortality trends in Kazakhstan: insights from a million of deaths from 2014 to 2022

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月3日

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  • Temirgali Aimyshev,
  • Gulnur Zhakhina,
  • Sauran Yerdessov,
  • Ruslan Akhmedullin,
  • Dinara Galiyeva,
  • Kuanysh Yergaliyev,
  • Antonio Sarria-Santamera,
  • Yuliya Semenova,
  • Abduzhappar Gaipov

摘要

Background

Kazakhstan’s healthcare system and population health have changed significantly between 2014 and 2022, especially due to the COVID-19 pandemic. This study analyzes mortality trends during this period to better understand the health challenges and regional differences that have emerged, addressing a gap in comprehensive research.

Methods

We analyzed mortality data from Kazakhstan’s Unified National Electronic Health System (2014–2022), calculating age-standardized mortality rates and years of life lost. Regional trends were assessed using linear regression.

Results

Overall mortality increased from 550.84 to 678.37 per 100,000 between 2014–2022, with significant regional variations. “Other disorders of the brain” emerged as a leading cause of premature mortality. COVID-19 significantly disrupted mortality patterns in 2020–2021. Mortality rates were consistently higher in males across most age groups, with a sharp increase after age 55, while “other disorders of the brain” emerged as a leading cause of premature mortality.

Conclusions

Kazakhstan faces evolving mortality challenges, with stark regional disparities and a concerning rise in neurological disorders. These findings underscore the need for targeted public health interventions and improved cause-of-death reporting.