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Background <p>The burden of low back pain (LBP) is increasing rapidly. This study aimed to analyze the temporal trends of the LBP burden in China from 1990 to 2021.</p> Methods <p>Data from the Global Burden of Disease (GBD) 2021 were used to examine the crude and age-standardized rates, along with their uncertainty interval (UI), for incidence, prevalence and disability adjusted life years (DALYs) per 100,000 for LBP, stratified by sex. The joinpoint regression model was applied to calculate the annual percent change (APC) and corresponding 95% confidence interval (<i>CI</i>) for the LBP burden. Additionally, an age-period-cohort analysis was conducted to assess the temporal trends in the LBP burden.</p> Results <p>In 2021, LBP affected 100,093,745 individuals in China. The crude incidence, prevalence and DALYs rates were 3.05% (95% UI: 2.64–3.46%), 7.04% (95% UI: 6.12–7.94%) and 794.08 per 100,000 (95% UI: 557.48–1077.36), respectively. From 1990 to 2021, the age-standardized incidence, prevalence and DALYs rates declined annually by 0.71% (95% <i>CI</i>: 0.67–0.75%), 0.79% (95% <i>CI</i>: 0.75–0.83%), and 0.79% (95% <i>CI</i>: 0.75–0.84%), respectively. The LBP burden was higher in females than in males, with incidence rates rising with age. From the age of 45 onward, women exhibited significantly higher incidence rates than men. Over the past three decades, both period-specific and cohort-specific LBP incidence showed a downward trend.</p> Conclusion <p>LBP remains a substantial public health burden in China, with variations across sex, age, period and cohort. Targeted healthcare policies and resource allocation should be prioritized for high-risk populations, particularly older adults and females.</p>

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Temporal trends of low back pain burden and joinpoint and age-period-cohort analysis in China from 1990 to 2021

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月30日

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  • Bo Liang,
  • Yue Wei,
  • Heming Pei,
  • Xiaoxuan Liang,
  • Gong Chen,
  • Lijun Pei

摘要

Background

The burden of low back pain (LBP) is increasing rapidly. This study aimed to analyze the temporal trends of the LBP burden in China from 1990 to 2021.

Methods

Data from the Global Burden of Disease (GBD) 2021 were used to examine the crude and age-standardized rates, along with their uncertainty interval (UI), for incidence, prevalence and disability adjusted life years (DALYs) per 100,000 for LBP, stratified by sex. The joinpoint regression model was applied to calculate the annual percent change (APC) and corresponding 95% confidence interval (CI) for the LBP burden. Additionally, an age-period-cohort analysis was conducted to assess the temporal trends in the LBP burden.

Results

In 2021, LBP affected 100,093,745 individuals in China. The crude incidence, prevalence and DALYs rates were 3.05% (95% UI: 2.64–3.46%), 7.04% (95% UI: 6.12–7.94%) and 794.08 per 100,000 (95% UI: 557.48–1077.36), respectively. From 1990 to 2021, the age-standardized incidence, prevalence and DALYs rates declined annually by 0.71% (95% CI: 0.67–0.75%), 0.79% (95% CI: 0.75–0.83%), and 0.79% (95% CI: 0.75–0.84%), respectively. The LBP burden was higher in females than in males, with incidence rates rising with age. From the age of 45 onward, women exhibited significantly higher incidence rates than men. Over the past three decades, both period-specific and cohort-specific LBP incidence showed a downward trend.

Conclusion

LBP remains a substantial public health burden in China, with variations across sex, age, period and cohort. Targeted healthcare policies and resource allocation should be prioritized for high-risk populations, particularly older adults and females.