<p>Work-family practices are defined as instruments which are used to facilitate reconciliation between work and family. However, research regarding the role of boundary management in shaping such interconnection is still needed. Based on border theory, this study aims to explore boundary control and work-family segmentation enactment as mechanisms to explain the relationship between work-family practices and work-family relationship (conflict and enrichment). The effect was evaluated through a two-wave data collection from 222 Portuguese bank employees. We observed that boundary control fully mediates the relationship between work-family practices and work-family conflict and partially mediates this relationship with work-family enrichment. Moreover, work-family segmentation enactment moderates the relationship between work-family practices and boundary control, weakening this relationship. Taking these results together, this study adds that employees’ boundary management strategies were imperative to explain and support the relationship between work-family practices and work-family relationship. The findings reveal the importance of work-family practices, along with the prominence of border theory for the field and offer implications for future research and organizational practice.</p>