Background <p>In Uganda, many people self-medicate and the practice raises important questions about access to healthcare, patient choices, and the increasing prevalence of antimicrobial resistance. This systematic review and meta-analysis investigated the prevalence and factors associated with self-medication in Uganda.</p> Methods <p>We searched Scopus, PubMed, and Embase databases, WHO AFRO, UNIPH registries, and Google Scholar search engine from inception to November 2024 using the algorithm “Self-Medication” AND “Uganda”. Twenty-two eligible studies were included while adhering to the preferred reporting items for systematic reviews and meta-analysis (PRISMA).</p> Results <p>A total of 9113 participants were represented across different demographics and regions of Uganda. Our analysis revealed a 55.63% (95%CI [40.40; 70.66] pooled prevalence of self-medication in Uganda. Antibiotics are&#xa0;the commonly self-medicated drugs and ease of access to medications, perceived cost effectiveness, long hospital waiting time, home storage of drugs (leftovers), and perceptions of minor illnesses were key contributors to self-medication behaviour.</p> Conclusion <p>At least 1 in 2 Ugandans self-medicate and antibiotics constitute the dominant self-medicated drugs compounding the situation in an era of antimicrobial resistance. Awareness campaigns on the dangers of self-medication will be timely.</p>

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The nature of self-medication in Uganda: a systematic review and meta-analysis

  • Danladi Makeri,
  • Priscilla Peter Dilli,
  • Theophilus Pius,
  • Naheem Adekilekun Tijani,
  • Abdullateef Afolabi Opeyemi,
  • Kadai Alhaji Lawan,
  • Shango Patience Emmanuel Jakheng,
  • Reagan Muhwezi,
  • Ambrose Shabohurira,
  • Ibe Michael Usman,
  • Ezera Agwu

摘要

Background

In Uganda, many people self-medicate and the practice raises important questions about access to healthcare, patient choices, and the increasing prevalence of antimicrobial resistance. This systematic review and meta-analysis investigated the prevalence and factors associated with self-medication in Uganda.

Methods

We searched Scopus, PubMed, and Embase databases, WHO AFRO, UNIPH registries, and Google Scholar search engine from inception to November 2024 using the algorithm “Self-Medication” AND “Uganda”. Twenty-two eligible studies were included while adhering to the preferred reporting items for systematic reviews and meta-analysis (PRISMA).

Results

A total of 9113 participants were represented across different demographics and regions of Uganda. Our analysis revealed a 55.63% (95%CI [40.40; 70.66] pooled prevalence of self-medication in Uganda. Antibiotics are the commonly self-medicated drugs and ease of access to medications, perceived cost effectiveness, long hospital waiting time, home storage of drugs (leftovers), and perceptions of minor illnesses were key contributors to self-medication behaviour.

Conclusion

At least 1 in 2 Ugandans self-medicate and antibiotics constitute the dominant self-medicated drugs compounding the situation in an era of antimicrobial resistance. Awareness campaigns on the dangers of self-medication will be timely.