Background <p>Medical anxiety is common in the pediatric population. Anxiety may trigger persistent negative emotions regarding medical care, cause decreased cooperation during procedures, and lead to higher reports of post-procedure pain. Teddy Bear Hospital (TBH) events may reduce pediatric anxiety related to health care visits by providing exposure to medical professionals and simulating procedures in a play environment. Literature on the effectiveness of such events is currently limited. We aimed to assess the effectiveness of a TBH-modelled event, the Teddy Bear Bash, in reducing pediatric reports of medical anxiety.</p> Methods <p>In a prospective cohort study, we surveyed 69 parents/guardians and 68 children during attendance at the Teddy Bear Bash in Saskatoon, Saskatchewan. Surveys were completed pre-event, immediately post-event, and 4 weeks after the event. Surveys assessed comfort level with medical care, reasons for medical anxiety, and improvements in either post-event.</p> Results <p>74.4% of parents/guardians reported subjective improvement in their child’s medical anxiety post-event, with 34.9% of these identifying a lasting change at 4-week follow-up. A statistically significant positive change in pediatric reports of feelings towards health care workers was demonstrated post-event (Z = -3.002, <i>p</i> = 0.003). Fears related to medical appointments in the pediatric population were decreased post-event, most markedly in concerns related to receiving an injection (a 31% decrease in percent responses). However, improvement of anxiety-related behaviours during medical appointments post-event was not clearly elicited.</p> Conclusions <p>Our findings suggest the Teddy Bear Bash is beneficial in promoting subjective reports of decreased medical-related anxiety in children. Exposure to the Teddy Bear Bash encourages a positive change in feelings toward health care workers by pediatric participants. These findings can likely be extrapolated to other TBH-type events.</p>