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Objective <p>To investigate the key clinical diagnostic and therapeutic points, challenges and corresponding strategies for duodenal perforation complicated with recurrent gastrointestinal bleeding in children, and to provide a clinical reference for managing this rare pediatric acute critical condition.</p> Methods <p>The clinical data of a 2-year-and-7-month-old female child with duodenal perforation and recurrent gastrointestinal bleeding were retrospectively analyzed. A systematic review and analysis were conducted from the perspectives of etiology, diagnosis, treatment and postoperative management, combined with relevant domestic and foreign literature over the past decade.</p> Results <p>A 2-year-and-7-month-old Chinese female child presented with viral enteritis initially, which progressed to duodenal perforation complicated with recurrent gastrointestinal bleeding. She received sequential interventions including duodenal perforation repair, gastroscopic exploration, gastrointestinal reconstruction, and transcatheter gastroduodenal artery embolization. Through whole-course multidisciplinary team (MDT) collaboration and refined comprehensive supportive therapy, the child achieved complete recovery with no recurrent bleeding.</p> Conclusion <p>The diagnosis and treatment of duodenal perforation complicated with recurrent gastrointestinal bleeding in children should focus on the core features of pediatric physiological particularities, etiological complexity, age-stage specificity and targeted management of clinical challenges. Adopting multimodal localization approaches, rationally selecting therapeutic regimens and relying on whole-course MDT collaboration can effectively reduce the risk of rebleeding and improve the prognosis of affected children.</p>

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Multidisciplinary approach for treatment of duodenal perforation complicated with gastrointestinal hemorrhage in pediatric patient and relevant literature review

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年6月25日

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  • Rongkun Zhu,
  • Yanan Zhang,
  • Jingjing Liu,
  • Di Wang,
  • Xiaoxuan Ma,
  • Qian Dong,
  • Xiwei Hao

摘要

Objective

To investigate the key clinical diagnostic and therapeutic points, challenges and corresponding strategies for duodenal perforation complicated with recurrent gastrointestinal bleeding in children, and to provide a clinical reference for managing this rare pediatric acute critical condition.

Methods

The clinical data of a 2-year-and-7-month-old female child with duodenal perforation and recurrent gastrointestinal bleeding were retrospectively analyzed. A systematic review and analysis were conducted from the perspectives of etiology, diagnosis, treatment and postoperative management, combined with relevant domestic and foreign literature over the past decade.

Results

A 2-year-and-7-month-old Chinese female child presented with viral enteritis initially, which progressed to duodenal perforation complicated with recurrent gastrointestinal bleeding. She received sequential interventions including duodenal perforation repair, gastroscopic exploration, gastrointestinal reconstruction, and transcatheter gastroduodenal artery embolization. Through whole-course multidisciplinary team (MDT) collaboration and refined comprehensive supportive therapy, the child achieved complete recovery with no recurrent bleeding.

Conclusion

The diagnosis and treatment of duodenal perforation complicated with recurrent gastrointestinal bleeding in children should focus on the core features of pediatric physiological particularities, etiological complexity, age-stage specificity and targeted management of clinical challenges. Adopting multimodal localization approaches, rationally selecting therapeutic regimens and relying on whole-course MDT collaboration can effectively reduce the risk of rebleeding and improve the prognosis of affected children.