Scholarlink

Objective <p>Cough variant asthma (CVA) is a specific asthma phenotype, and wheezing or abnormal breathing sounds are rarely heard in CVA patients during traditional auscultation. This study aimed to use a standardized electronic stethoscope to assess whether there are differences in breath sounds between healthy children and children with CVA.</p> Methods <p>Thirty-five&#xa0;healthy children (476 segments of the inspiratory phase) and nineteen children with CVA (244 segments of the inspiratory phase) participated. A comparative analysis was conducted on the breath sound parameters, including the area under the curve (AUC), the secant slope, and the power of the sound spectrum (decibel, dB), between healthy children and children with CVA. For further comparative analysis, children with CVA were divided into two subgroups based on allergy grades and pulmonary function (PF) statuses: allergy grade &lt; = 2 groups vs. allergy grade &gt; = 3 group, normal PF group vs. abnormal PF group. Statistical analyses were completed using the SPSS software.</p> Results <p>This study demonstrated that the AUC, the secant slope, and the dB values in children with CVA were higher than those in healthy children. Children with CVA whose allergy grade &gt; = 3 had a higher secant slope value at 700–1700&#xa0;Hz and higher dB values at 1100&#xa0;Hz, 1300&#xa0;Hz, and 1500&#xa0;Hz. In the abnormal PF group, the dB values at 1300&#xa0;Hz and 1700&#xa0;Hz are lower in children with CVA.</p> Conclusions <p>This study proved that children with CVA have abnormal sounds that traditional auscultation methods cannot identify. Meanwhile, both allergy grade and PF status can affect breath sounds.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Difference of breath sound spectrum between healthy children and children with cough variant asthma

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月3日

查看全文
  • Di Lv,
  • Chaoshan Hu,
  • Jing Liu,
  • Lijuan Tang,
  • Yuanmei Chen,
  • Fang Ye,
  • Chao Wang,
  • Yiqiang Fan,
  • Qi Zhang

摘要

Objective

Cough variant asthma (CVA) is a specific asthma phenotype, and wheezing or abnormal breathing sounds are rarely heard in CVA patients during traditional auscultation. This study aimed to use a standardized electronic stethoscope to assess whether there are differences in breath sounds between healthy children and children with CVA.

Methods

Thirty-five healthy children (476 segments of the inspiratory phase) and nineteen children with CVA (244 segments of the inspiratory phase) participated. A comparative analysis was conducted on the breath sound parameters, including the area under the curve (AUC), the secant slope, and the power of the sound spectrum (decibel, dB), between healthy children and children with CVA. For further comparative analysis, children with CVA were divided into two subgroups based on allergy grades and pulmonary function (PF) statuses: allergy grade < = 2 groups vs. allergy grade > = 3 group, normal PF group vs. abnormal PF group. Statistical analyses were completed using the SPSS software.

Results

This study demonstrated that the AUC, the secant slope, and the dB values in children with CVA were higher than those in healthy children. Children with CVA whose allergy grade > = 3 had a higher secant slope value at 700–1700 Hz and higher dB values at 1100 Hz, 1300 Hz, and 1500 Hz. In the abnormal PF group, the dB values at 1300 Hz and 1700 Hz are lower in children with CVA.

Conclusions

This study proved that children with CVA have abnormal sounds that traditional auscultation methods cannot identify. Meanwhile, both allergy grade and PF status can affect breath sounds.