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<p>A preterm infant who previously experienced Candida septicemia at 18&#xa0;days of life and was treated with standard antifungal therapy presented one month later with signs of multifocal osteomyelitis and arthritis. Causative <i>Candida albicans</i> was detected by metagenomic next-generation sequencing (mNGS). Since the symptoms of neonatal candidal osteomyelitis are typically insidious, early diagnosis and appropriate treatment are crucial. Moreover, incision and drainage of the affected joint are essential for a favorable prognosis.</p>

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Case report: a case of neonatal Candida osteomyelitis with septic arthritis and literature review

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年1月5日

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  • Yuqi Zhao,
  • Lirong Dai,
  • Lili Wang,
  • Li Wang

摘要

A preterm infant who previously experienced Candida septicemia at 18 days of life and was treated with standard antifungal therapy presented one month later with signs of multifocal osteomyelitis and arthritis. Causative Candida albicans was detected by metagenomic next-generation sequencing (mNGS). Since the symptoms of neonatal candidal osteomyelitis are typically insidious, early diagnosis and appropriate treatment are crucial. Moreover, incision and drainage of the affected joint are essential for a favorable prognosis.