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Objective <p>To explore the blood level and its change trend of primary and secondary school students aged 6 ~ 18&#xa0;years in high altitude area (4300&#xa0;m above sea level), and to provide a reference basis for the establishment of reference interval of blood cell analysis for children in high altitude area.</p> Methods <p>Primary and secondary school students aged 6 to 18 in Ali, Tibet (4300&#xa0;m above sea level) were used as the study subjects. Routine blood tests were performed during routine physical examinations to compare the blood levels of primary and secondary school students of different genders in the four age groups of 6–9, 10–12, 13–15, and 16–18&#xa0;years old and to analyze the trends of changes with age and gender.</p> Results <p>The differences in the routine blood indicators of WBC, Lymph, Mid, Mid%, MCV, MCH, MPV, P-LCC, and P-LCR among primary and secondary school students at high altitudes were statistically significant in different age groups (<i>P</i> &lt; 0.05); the routine blood indicators of Lymph, MCV, MCH, and RDW-CV among primary and secondary school students of different genders at high altitude were statistically significant in the age groups of 6–9&#xa0;years old and the age groups of 16–18&#xa0;years old and the age groups of 10–12&#xa0;years old, 13–15&#xa0;years old and 16–18&#xa0;years old, respectively. MCV, MCH, MCHC and RDW-CV at the age of 10 ~ 12&#xa0;years, NEUT, RBC, MCV, MCH, MCHC, RDW-SD and PDW at the age of 13 ~ 15&#xa0;years, and the differences of WBC, NEUT, RBC, HGB, HCT, MCHC, MPV, PDW, P-LCC and P-LCR in male and female students at the age of 16 ~ 18&#xa0;years are statistically significant (<i>P</i> &lt; 0.05); WBC, LYM, Mid, Mid% and PLT showed a linear decreasing trend with age in both sexes (<i>P</i> &lt; 0.01), and HGB, MCV, MCH, RDW-SD, MPV, PDW and P-LCR showed a linear increasing trend with age in both sexes (<i>P</i> &lt; 0.01).</p> Conclusion <p>The blood routine indexes of primary and secondary school students in high altitude areas differed between different age groups and genders, and influencing factors such as age and gender should be considered when formulating reference intervals for blood cells of children in high altitude areas.</p>

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Analysis of blood test results of primary and secondary school students in high altitude areas

  • 期刊论文

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  • 发表日期：

    2025年3月18日

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  • Mingxia Zhang,
  • Shuai Ma,
  • Yuyan Chen,
  • Boshen Li,
  • Xingyi Bao,
  • Peng Tian,
  • Rong Wang,
  • Wenbin Li,
  • Shanshan Kang

摘要

Objective

To explore the blood level and its change trend of primary and secondary school students aged 6 ~ 18 years in high altitude area (4300 m above sea level), and to provide a reference basis for the establishment of reference interval of blood cell analysis for children in high altitude area.

Methods

Primary and secondary school students aged 6 to 18 in Ali, Tibet (4300 m above sea level) were used as the study subjects. Routine blood tests were performed during routine physical examinations to compare the blood levels of primary and secondary school students of different genders in the four age groups of 6–9, 10–12, 13–15, and 16–18 years old and to analyze the trends of changes with age and gender.

Results

The differences in the routine blood indicators of WBC, Lymph, Mid, Mid%, MCV, MCH, MPV, P-LCC, and P-LCR among primary and secondary school students at high altitudes were statistically significant in different age groups (P < 0.05); the routine blood indicators of Lymph, MCV, MCH, and RDW-CV among primary and secondary school students of different genders at high altitude were statistically significant in the age groups of 6–9 years old and the age groups of 16–18 years old and the age groups of 10–12 years old, 13–15 years old and 16–18 years old, respectively. MCV, MCH, MCHC and RDW-CV at the age of 10 ~ 12 years, NEUT, RBC, MCV, MCH, MCHC, RDW-SD and PDW at the age of 13 ~ 15 years, and the differences of WBC, NEUT, RBC, HGB, HCT, MCHC, MPV, PDW, P-LCC and P-LCR in male and female students at the age of 16 ~ 18 years are statistically significant (P < 0.05); WBC, LYM, Mid, Mid% and PLT showed a linear decreasing trend with age in both sexes (P < 0.01), and HGB, MCV, MCH, RDW-SD, MPV, PDW and P-LCR showed a linear increasing trend with age in both sexes (P < 0.01).

Conclusion

The blood routine indexes of primary and secondary school students in high altitude areas differed between different age groups and genders, and influencing factors such as age and gender should be considered when formulating reference intervals for blood cells of children in high altitude areas.