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Background <p>We investigated the effect of long-term use of scleral contact lens (SL) on corneal endothelial parameters in patients with keratoconus (KC).</p> Methods <p>Specular microscopy (Konan Cell Check SL, Hyogo, Japan) imaging was performed on healthy subjects (control group) and patients with KC (KC group) who were long-term SL wearers using the center method. Specular microscopy measurements were taken for both the groups before and after SL use.</p> Results <p>The mean duration of SL use in the KC group was 5 ± 2 years. No significant differences in specular microscopy parameters were noted between the first and last examinations of the control and KC groups.</p> Conclusion <p>Corneal endothelial parameters were not affected in long-term SL wearers when the recommended fitting and usage practices were followed, suggesting that SL use is well tolerated by the corneal endothelium. However, further research involving larger cohorts is essential to confirm the long-term safety of SL use.</p>

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Long-term impact of scleral contact lens use on endothelial cell density in patients with moderate to advanced keratoconus

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月28日

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  • Cezmi Doğan,
  • Oğuzhan Kılıçarslan,
  • Fatma Burcu Özdemir,
  • Doğukan Atakan,
  • Burak Mergen

摘要

Background

We investigated the effect of long-term use of scleral contact lens (SL) on corneal endothelial parameters in patients with keratoconus (KC).

Methods

Specular microscopy (Konan Cell Check SL, Hyogo, Japan) imaging was performed on healthy subjects (control group) and patients with KC (KC group) who were long-term SL wearers using the center method. Specular microscopy measurements were taken for both the groups before and after SL use.

Results

The mean duration of SL use in the KC group was 5 ± 2 years. No significant differences in specular microscopy parameters were noted between the first and last examinations of the control and KC groups.

Conclusion

Corneal endothelial parameters were not affected in long-term SL wearers when the recommended fitting and usage practices were followed, suggesting that SL use is well tolerated by the corneal endothelium. However, further research involving larger cohorts is essential to confirm the long-term safety of SL use.