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Background <p>In the present study, we aimed to comprehensively describe the full clinical course of dead bag syndrome (DBS) presenting 17 months after cataract surgery, and to elucidate its clinical characteristics, histopathological features.</p> Case presentation <p>A 55-year-old man presented with progressive blurred vision in his left eye 17 months following an uncomplicated cataract extraction. Ophthalmic examination revealed a lax, translucent capsular bag accompanied by partial dislocation of the intraocular lens (IOL)–capsular bag complex. Histopathological analysis showed extensive depletion of lens epithelial cells (LECs), multilayer delamination of the capsular bag, and markedly reduced fibronectin expression. The patient subsequently underwent removal of the displaced IOL and scleral-sutured implantation of a new IOL, which led to substantial postoperative visual recovery.</p> Conclusion <p>This case indicated that DBS could manifest within a relatively short postoperative interval. Histopathological analysis showed structural alterations of the capsular bag consistent with DBS following cataract surgery. Accordingly, DBS should be recognized as a potential complication and carefully considered during routine postoperative surveillance following cataract surgery.</p>

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Early-onset dead bag syndrome following cataract surgery: a case report with clinical and histopathological findings

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月26日

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  • Yifan Jiang,
  • Huiling Zhao,
  • Xiaogang Hong,
  • Zhe Xu,
  • Jijian Lin,
  • Yuchen Lin,
  • Wen Xu

摘要

Background

In the present study, we aimed to comprehensively describe the full clinical course of dead bag syndrome (DBS) presenting 17 months after cataract surgery, and to elucidate its clinical characteristics, histopathological features.

Case presentation

A 55-year-old man presented with progressive blurred vision in his left eye 17 months following an uncomplicated cataract extraction. Ophthalmic examination revealed a lax, translucent capsular bag accompanied by partial dislocation of the intraocular lens (IOL)–capsular bag complex. Histopathological analysis showed extensive depletion of lens epithelial cells (LECs), multilayer delamination of the capsular bag, and markedly reduced fibronectin expression. The patient subsequently underwent removal of the displaced IOL and scleral-sutured implantation of a new IOL, which led to substantial postoperative visual recovery.

Conclusion

This case indicated that DBS could manifest within a relatively short postoperative interval. Histopathological analysis showed structural alterations of the capsular bag consistent with DBS following cataract surgery. Accordingly, DBS should be recognized as a potential complication and carefully considered during routine postoperative surveillance following cataract surgery.