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Background <p>The purpose of this study was to provide a case report of a patient with uveitis-glaucoma-hyphema-vitreous hemorrhage (UGH plus) syndrome with intraocular lens (IOL) scleral fixation who presented with recurrent decreased vision and to discuss potential risk factors and treatment options.</p> Case presentation <p>A 54-year-old man with a history of multiple ocular traumas and surgeries underwent IOL reposition surgery (scleral fixation) in his right eye in July 2020. He complained of having blurred vision after rubbing his right eye in February 2023. We diagnosed him with UGH plus syndrome on the basis of successive anterior chamber inflammation, elevated intraocular pressure (IOP), hyphema and vitreous hemorrhage. Ultrasound biomicroscopy revealed a concave iris. Laser peripheral iridotomy (LPI) effectively controls UGH plus syndrome.</p> Conclusions <p>We reported the successful management of UGH plus syndrome with a scleral-fixed IOL via the LPI. Given the increasing prevalence of IOL implantation, great importance should be attached to the possibility of UGH syndrome, especially in patients with high-risk factors.</p>

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Laser peripheral iridotomy for treating recurrent uveitis-glaucoma-hyphema plus syndrome with a scleral fixed intraocular lens: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月21日

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  • Fan Yang,
  • Peimin Lin,
  • Dongjin Qian,
  • Jie Xu,
  • Ao Miao,
  • Jiahui Chen,
  • Tianyu Zheng

摘要

Background

The purpose of this study was to provide a case report of a patient with uveitis-glaucoma-hyphema-vitreous hemorrhage (UGH plus) syndrome with intraocular lens (IOL) scleral fixation who presented with recurrent decreased vision and to discuss potential risk factors and treatment options.

Case presentation

A 54-year-old man with a history of multiple ocular traumas and surgeries underwent IOL reposition surgery (scleral fixation) in his right eye in July 2020. He complained of having blurred vision after rubbing his right eye in February 2023. We diagnosed him with UGH plus syndrome on the basis of successive anterior chamber inflammation, elevated intraocular pressure (IOP), hyphema and vitreous hemorrhage. Ultrasound biomicroscopy revealed a concave iris. Laser peripheral iridotomy (LPI) effectively controls UGH plus syndrome.

Conclusions

We reported the successful management of UGH plus syndrome with a scleral-fixed IOL via the LPI. Given the increasing prevalence of IOL implantation, great importance should be attached to the possibility of UGH syndrome, especially in patients with high-risk factors.