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Background <p>To compare the distribution characteristics of corneal biomechanics and tomographic parameters for different corneal diameter (CD) in Chinese patients.</p> Methods <p>A retrospective cohort study of 403 consecutive patients without ectasia who underwent binocular corneal refractive surgery and were followed up for more than 2 years. All patients underwent a preoperative corneal tomography using Pentacam and corneal biomechanics using Corvis-ST.</p> Results <p>Significant differences were observed in the Stiffness parameter at first applanation (SP-A1), Ambrosio relational thickness to the horizontal profile (ARTh), Belin/Ambrosio enhanced ectasia total deviation index (BAD-D), Corvis Biomechanical Index (CBI), and Tomographic and Biomechanical Index (TBI) indicators among the CD ≤ 11.0&#xa0;mm, 11.0&#xa0;mm &lt; CD ≤ 11.5&#xa0;mm, 11.5&#xa0;mm &lt; CD &lt; 12.0&#xa0;mm, and CD ≥ 12.0&#xa0;mm groups (all <i>P</i> &lt; 0.05). CD was negatively correlated with BAD-D, CBI, and TBI (<i>r</i> = -0.475, -0.269 and − 0.237, all <i>P</i> &lt; 0.05); Multiple linear regression analysis showed that TBI was negatively correlated with CD, SP-A1, and ARTh (R<sup>2</sup> = 0.12, <i>p</i>&lt;0.001).</p> Conclusions <p>CD may correlated with the biomechanical results, where smaller CD is often associated with higher BAD, CBI, and TBI values. CD-specific thresholds for biomechanical indices may reduce overdiagnosis of keratoconus in small corneas.</p>

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Corneal biomechanics and tomographic parameters for different corneal diameters in Chinese patients with myopia

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  • 发表日期：

    2025年8月25日

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  • Li Li,
  • Qizhi Zhou

摘要

Background

To compare the distribution characteristics of corneal biomechanics and tomographic parameters for different corneal diameter (CD) in Chinese patients.

Methods

A retrospective cohort study of 403 consecutive patients without ectasia who underwent binocular corneal refractive surgery and were followed up for more than 2 years. All patients underwent a preoperative corneal tomography using Pentacam and corneal biomechanics using Corvis-ST.

Results

Significant differences were observed in the Stiffness parameter at first applanation (SP-A1), Ambrosio relational thickness to the horizontal profile (ARTh), Belin/Ambrosio enhanced ectasia total deviation index (BAD-D), Corvis Biomechanical Index (CBI), and Tomographic and Biomechanical Index (TBI) indicators among the CD ≤ 11.0 mm, 11.0 mm < CD ≤ 11.5 mm, 11.5 mm < CD < 12.0 mm, and CD ≥ 12.0 mm groups (all P < 0.05). CD was negatively correlated with BAD-D, CBI, and TBI (r = -0.475, -0.269 and − 0.237, all P < 0.05); Multiple linear regression analysis showed that TBI was negatively correlated with CD, SP-A1, and ARTh (R2 = 0.12, p<0.001).

Conclusions

CD may correlated with the biomechanical results, where smaller CD is often associated with higher BAD, CBI, and TBI values. CD-specific thresholds for biomechanical indices may reduce overdiagnosis of keratoconus in small corneas.