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Background <p>To explore the spatial distribution and associated factors of White and Dark Without Pressure lesions in myopic patients using ultra-widefield fundus imaging.</p> Methods <p>This retrospective, observational study evaluated 2,940 eyes from 1,470 patients who underwent refractive surgery. Ultra-widefield fundus imaging was used to identify and map the distribution of white and dark without pressure lesions across 12 retinal sectors. Correlations between the incidence of these lesions, their location, axial length, and the number of affected sectors were analyzed.</p> Results <p>White and dark without pressure lesions were present in 907 eyes (30.8%), with a significant association between increased axial length and higher incidence of white and dark without pressure (<i>P</i> &lt; 0.001). Lesions were predominantly located in the temporal retina, specifically in the inferotemporal and superotemporal sectors. Longer axial length and younger age were both associated with a higher number of affected sectors and a more posterior localization of lesions.</p> Conclusion <p>Axial elongation is significantly correlated with both the occurrence and posterior localization of white and dark without pressure lesions, as well as a higher number of affected sectors in myopic eyes. Ultra-widefield fundus imaging offers a comprehensive perspective on these retinal changes, providing valuable insights into the pathophysiology of white and dark without pressure.</p>

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Axial elongation and the spatial distribution of white and dark without pressure in myopic eyes: insights from ultra-widefield imaging

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月25日

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  • Szy Yann Chan,
  • Chung Ting Pan,
  • Hai Ping Li,
  • Yue Guo Chen

摘要

Background

To explore the spatial distribution and associated factors of White and Dark Without Pressure lesions in myopic patients using ultra-widefield fundus imaging.

Methods

This retrospective, observational study evaluated 2,940 eyes from 1,470 patients who underwent refractive surgery. Ultra-widefield fundus imaging was used to identify and map the distribution of white and dark without pressure lesions across 12 retinal sectors. Correlations between the incidence of these lesions, their location, axial length, and the number of affected sectors were analyzed.

Results

White and dark without pressure lesions were present in 907 eyes (30.8%), with a significant association between increased axial length and higher incidence of white and dark without pressure (P < 0.001). Lesions were predominantly located in the temporal retina, specifically in the inferotemporal and superotemporal sectors. Longer axial length and younger age were both associated with a higher number of affected sectors and a more posterior localization of lesions.

Conclusion

Axial elongation is significantly correlated with both the occurrence and posterior localization of white and dark without pressure lesions, as well as a higher number of affected sectors in myopic eyes. Ultra-widefield fundus imaging offers a comprehensive perspective on these retinal changes, providing valuable insights into the pathophysiology of white and dark without pressure.