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Background <p>Cervical cancer remains a significant public health challenge for women in Africa. This study aimed to quantify the current burden of cervical cancer across the continent using the most recent estimates from the Global Cancer Observatory (GLOBOCAN) 2022.</p> Methods <p>Data were obtained from GLOBOCAN 2022. Age-standardized incidence rates (ASIR) and age-standardized mortality rates (ASMR) per 100,000 person-years were calculated using direct standardization with the Segi–Doll world standard population. Pearson’s correlation analysis was applied to examine associations between the Human Development Index (HDI) and cervical cancer incidence and mortality. Future numbers of cases and deaths through 2050 were projected based on global population forecasts.</p> Results <p>In 2022, an estimated 125,699 new cervical cancer cases and 80,614 deaths occurred in Africa. Nigeria recorded the highest numbers of incident cases (13,676) and deaths (7,093). The highest ASIR was observed in Eswatini (95.9 per 100,000), while Malawi exhibited the highest ASMR (54.1 per 100,000). Mortality rates increased progressively with age and rose sharply among individuals aged 75 years and older. A negative association was identified between HDI and mortality rates. Projections indicate that Nigeria and Tanzania will experience the largest future burden, with Equatorial Guinea, Tanzania, and Zambia facing increases exceeding 200% in incidence and 210% in mortality by 2050.</p> Conclusions <p>Cervical cancer mortality remains disproportionately high in countries with lower socioeconomic development. Targeted and timely interventions in these settings are essential to curb the projected escalation of disease burden.</p>

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Geographic and demographic patterns of cervical cancer in Africa using GLOBOCAN 2022

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月18日

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  • Xiaoli Zhou,
  • Hong Xu,
  • Yu Fu,
  • Qiqin Nie,
  • Baohua Zhang,
  • Xiaoya Guo,
  • Mingzhu Hu

摘要

Background

Cervical cancer remains a significant public health challenge for women in Africa. This study aimed to quantify the current burden of cervical cancer across the continent using the most recent estimates from the Global Cancer Observatory (GLOBOCAN) 2022.

Methods

Data were obtained from GLOBOCAN 2022. Age-standardized incidence rates (ASIR) and age-standardized mortality rates (ASMR) per 100,000 person-years were calculated using direct standardization with the Segi–Doll world standard population. Pearson’s correlation analysis was applied to examine associations between the Human Development Index (HDI) and cervical cancer incidence and mortality. Future numbers of cases and deaths through 2050 were projected based on global population forecasts.

Results

In 2022, an estimated 125,699 new cervical cancer cases and 80,614 deaths occurred in Africa. Nigeria recorded the highest numbers of incident cases (13,676) and deaths (7,093). The highest ASIR was observed in Eswatini (95.9 per 100,000), while Malawi exhibited the highest ASMR (54.1 per 100,000). Mortality rates increased progressively with age and rose sharply among individuals aged 75 years and older. A negative association was identified between HDI and mortality rates. Projections indicate that Nigeria and Tanzania will experience the largest future burden, with Equatorial Guinea, Tanzania, and Zambia facing increases exceeding 200% in incidence and 210% in mortality by 2050.

Conclusions

Cervical cancer mortality remains disproportionately high in countries with lower socioeconomic development. Targeted and timely interventions in these settings are essential to curb the projected escalation of disease burden.