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Objective <p>This study investigates the relationship between cognitive function and depression in cancer patients receiving chemotherapy.</p> Methods <p>A cross-sectional study design was employed, involving 80 cancer patients undergoing chemotherapy. Data were collected using the Socio-Demographic Information Form, the Functional Assessment of Cancer Therapy–Cognitive Function (FACT-Cog), and the Beck Depression Inventory (BDI). Assessments were conducted prior to the second cycle of chemotherapy.</p> Results <p>Among participants, 72.8% were female and 47.5% aged 40–50. Moderate depressive symptoms were most common (45%). Cognitive dysfunction was inversely correlated with depression (<i>r</i> = -0.525, <i>p</i> &lt; 0.001). Low income significantly predicted lower cognitive scores (<i>p</i> = 0.01).</p> Conclusion <p>Chemotherapy patients exhibit cognitive decline and elevated depression levels. Socioeconomic status exacerbates these effects. Psychosocial interventions should be integrated into oncological rehabilitation.</p>

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Cognitive dysfunction and depression in chemotherapy patients: a cross-sectional study from Turkey

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月30日

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  • Elif Dinler,
  • Deniz Kocamaz,
  • Mürşide Özpineci,
  • Sibel Polat Olca,
  • Sema İçel,
  • Mustafa Yıldırım

摘要

Objective

This study investigates the relationship between cognitive function and depression in cancer patients receiving chemotherapy.

Methods

A cross-sectional study design was employed, involving 80 cancer patients undergoing chemotherapy. Data were collected using the Socio-Demographic Information Form, the Functional Assessment of Cancer Therapy–Cognitive Function (FACT-Cog), and the Beck Depression Inventory (BDI). Assessments were conducted prior to the second cycle of chemotherapy.

Results

Among participants, 72.8% were female and 47.5% aged 40–50. Moderate depressive symptoms were most common (45%). Cognitive dysfunction was inversely correlated with depression (r = -0.525, p < 0.001). Low income significantly predicted lower cognitive scores (p = 0.01).

Conclusion

Chemotherapy patients exhibit cognitive decline and elevated depression levels. Socioeconomic status exacerbates these effects. Psychosocial interventions should be integrated into oncological rehabilitation.