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Background <p>The physiology of bone marrow adipose tissue during pregnancy and lactation remains poorly understood.</p> Case presentation <p>In this exploratory single-subject magnetic resonance imaging study, we investigated the intensity of skull bone marrow before, during and after pregnancy of a 38-year-old primiparous woman.</p> Conclusion <p>We observed a curvilinear pattern of change. These preliminary findings require validation using quantitative fat imaging in larger cohorts and highlight the need for further research into maternal bone health during pregnancy and lactation.</p>

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Changes in human skull bone marrow during pregnancy and postpartum: an exploratory case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月20日

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  • Polona Kalc,
  • Eileen Luders,
  • Robert Dahnke

摘要

Background

The physiology of bone marrow adipose tissue during pregnancy and lactation remains poorly understood.

Case presentation

In this exploratory single-subject magnetic resonance imaging study, we investigated the intensity of skull bone marrow before, during and after pregnancy of a 38-year-old primiparous woman.

Conclusion

We observed a curvilinear pattern of change. These preliminary findings require validation using quantitative fat imaging in larger cohorts and highlight the need for further research into maternal bone health during pregnancy and lactation.