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<p>The aim of this report is to present a rare case of pre‑labour premature rupture of membranes (PPROM) in a patient in the second trimester of pregnancy, in which an association with a lower genital tract infection caused by <i>Trichomonas vaginalis</i> was observed. The patient was a 26‑year‑old woman, gravida 2, at 25 weeks of gestation, who presented with clinical complaints of abnormal vaginal discharge and fluid leakage.</p><p><?noindent??>Following a definitive diagnosis of trichomoniasis based on stained smear and culture findings, standard treatment with metronidazole was initiated. The treatment was effective, leading to complete resolution of maternal symptoms, full eradication of the infection, and a stable, viable fetal condition.</p><p><?noindent??>This case highlights the potential importance of timely identification and management of common sexually transmitted infections during pregnancy, as such infections may be associated with alterations in fetal membrane integrity and adverse pregnancy outcomes, although a causal relationship cannot be inferred from a single observational report.</p>

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Trichomoniasis associated with amniotic sac rupture in pregnancy: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月13日

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  • Hajar Ziaei Hezarjaribi,
  • Maliheh Ghasemi Tirtashi,
  • Marzieh Asadi

摘要

The aim of this report is to present a rare case of pre‑labour premature rupture of membranes (PPROM) in a patient in the second trimester of pregnancy, in which an association with a lower genital tract infection caused by Trichomonas vaginalis was observed. The patient was a 26‑year‑old woman, gravida 2, at 25 weeks of gestation, who presented with clinical complaints of abnormal vaginal discharge and fluid leakage.

Following a definitive diagnosis of trichomoniasis based on stained smear and culture findings, standard treatment with metronidazole was initiated. The treatment was effective, leading to complete resolution of maternal symptoms, full eradication of the infection, and a stable, viable fetal condition.

This case highlights the potential importance of timely identification and management of common sexually transmitted infections during pregnancy, as such infections may be associated with alterations in fetal membrane integrity and adverse pregnancy outcomes, although a causal relationship cannot be inferred from a single observational report.