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<p>Migraine aura manifests as various neurological symptoms, which may occur before, during, or persist throughout the headache phase. We report a case of a 30-year-old female patient whose initial symptoms included persistent bilateral photopsia and ophthalmoplegia, accompanied by headache, with a medical history spanning over four years. The duration of her auras was up to one month. After admission, through detailed inquiry into her medical history and extensive etiological screening, the patient was diagnosed with chronic migraine (CM). Following preventive treatment for CM, her symptoms significantly improved. This case serves to encourage neurologists to expand their diagnostic thinking in clinical practice. When encountering sudden and unexplained persistent neurological symptoms, the possibility of migraine with persistent aura should be considered.</p>

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Chronic migraine characterized by prolonged bilateral visual and brainstem aura: a case report and literature review

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月19日

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  • Xiaoshuang Li,
  • Tianshuang Gao,
  • Dong Qiu,
  • Yaqing Zhang,
  • Xueying Yu,
  • Hefei Tang,
  • Yonggang Wang

摘要

Migraine aura manifests as various neurological symptoms, which may occur before, during, or persist throughout the headache phase. We report a case of a 30-year-old female patient whose initial symptoms included persistent bilateral photopsia and ophthalmoplegia, accompanied by headache, with a medical history spanning over four years. The duration of her auras was up to one month. After admission, through detailed inquiry into her medical history and extensive etiological screening, the patient was diagnosed with chronic migraine (CM). Following preventive treatment for CM, her symptoms significantly improved. This case serves to encourage neurologists to expand their diagnostic thinking in clinical practice. When encountering sudden and unexplained persistent neurological symptoms, the possibility of migraine with persistent aura should be considered.